LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T PF477736
3.33
uM
LJP5
 72
hr
 658 566 3846 0.1473 -0.0288
Hs 578T PF562271
3.33
uM
LJP6
 72
hr
 658 1573 3846 0.4092 0.2872
Hs 578T PHA-665752
3.33
uM
LJP5
 72
hr
 658 3707 3846 0.9638 0.9564
Hs 578T PHA-793887
3.33
uM
LJP6
 72
hr
 658 534 3846 0.1388 -0.0390
Hs 578T PI103
3.33
uM
LJP6
 72
hr
 658 1230 3846 0.3198 0.1794
Hs 578T PLX-4720
3.33
uM
LJP5
 72
hr
 658 3690 3846 0.9596 0.9512
MCF7 Afatinib
3.33
uM
LJP6
 72
hr
 1209 3086 4093 0.7541 0.6510
Hs 578T QL-X-138
3.33
uM
LJP6
 72
hr
 658 1318 3846 0.3428 0.2071
Hs 578T QL-XII-47
3.33
uM
LJP6
 72
hr
 658 640 3846 0.1666 -0.0055
Hs 578T Radicicol
3.33
uM
LJP5
 72
hr
 658 687 3846 0.1788 0.0092
Hs 578T Radicicol
3.33
uM
LJP6
 72
hr
 658 686 3846 0.1785 0.0089
Hs 578T Seliciclib
3.33
uM
LJP5
 72
hr
 658 3388 3846 0.8811 0.8565
Hs 578T Ruxolitinib
3.33
uM
LJP5
 72
hr
 658 3559 3846 0.9254 0.9099
Hs 578T XL147
3.33
uM
LJP5
 72
hr
 658 3861 3846 1.0039 1.0047
Hs 578T Saracatinib
3.33
uM
LJP6
 72
hr
 658 2520 3846 0.6554 0.5842
Hs 578T Selumetinib
3.33
uM
LJP6
 72
hr
 658 1534 3846 0.3990 0.2749
Hs 578T Sirolimus
3.33
uM
LJP6
 72
hr
 658 2419 3846 0.6291 0.5526
Hs 578T Sorafenib
3.33
uM
LJP6
 72
hr
 658 3885 3846 1.0103 1.0124
Hs 578T SU11274
3.33
uM
LJP5
 72
hr
 658 3226 3846 0.8389 0.8056
Hs 578T Fedratinib
3.33
uM
LJP5
 72
hr
 658 1270 3846 0.3302 0.1919
Hs 578T TGX221
3.33
uM
LJP5
 72
hr
 658 3510 3846 0.9126 0.8946
Hs 578T Torin1
3.33
uM
LJP6
 72
hr
 658 748 3846 0.1947 0.0284
Hs 578T Torin2
3.33
uM
LJP5
 72
hr
 658 533 3846 0.1386 -0.0393
Hs 578T Tozasertib
3.33
uM
LJP5
 72
hr
 658 791 3846 0.2058 0.0418
Hs 578T Trametinib
3.33
uM
LJP5
 72
hr
 658 905 3846 0.2353 0.0774