LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A TGX221
10.0
uM
LJP5
72
hr
962 10603 10605 0.9998 0.9998
MCF 10A Torin1
10.0
uM
LJP6
72
hr
962 1262 10605 0.1190 0.0311
MCF 10A Torin2
10.0
uM
LJP5
72
hr
962 1277 10605 0.1204 0.0327
MCF 10A Tozasertib
10.0
uM
LJP5
72
hr
962 1266 10605 0.1194 0.0316
MCF 10A Trametinib
10.0
uM
LJP5
72
hr
962 1979 10605 0.1866 0.1055
MCF 10A TWS119
10.0
uM
LJP5
72
hr
962 1247 10605 0.1176 0.0296
MCF 10A Vemurafenib
10.0
uM
LJP5
72
hr
962 4165 10605 0.3928 0.3322
MCF 10A Withaferin A
10.0
uM
LJP5
72
hr
962 594 10605 0.0561 -0.0381
MCF 10A Withaferin A
10.0
uM
LJP6
72
hr
962 574 10605 0.0541 -0.0403
MCF 10A WYE-125132
10.0
uM
LJP6
72
hr
962 1427 10605 0.1346 0.0482
MCF 10A WZ3105
10.0
uM
LJP5
72
hr
962 185 10605 0.0175 -0.0806
MCF 10A XMD11-50
10.0
uM
LJP6
72
hr
962 1194 10605 0.1127 0.0241
MCF 10A Y39983
10.0
uM
LJP6
72
hr
962 4273 10605 0.4030 0.3434
MCF 10A YM 201636
10.0
uM
LJP5
72
hr
962 2670 10605 0.2518 0.1771
MCF 10A ZSTK474
10.0
uM
LJP6
72
hr
962 1349 10605 0.1273 0.0402