LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Dasatinib
3.33
uM
LJP5
 72
hr
 658 556 3846 0.1447 -0.0320
Hs 578T Dasatinib
3.33
uM
LJP6
 72
hr
 658 540 3846 0.1405 -0.0370
Hs 578T Foretinib
3.33
uM
LJP5
 72
hr
 658 1085 3846 0.2821 0.1339
Hs 578T R406
3.33
uM
LJP6
 72
hr
 658 1994 3846 0.5185 0.4190
Hs 578T Gefitinib
3.33
uM
LJP6
 72
hr
 658 3709 3846 0.9645 0.9572
Hs 578T Geldanamycin
3.33
uM
LJP5
 72
hr
 658 737 3846 0.1917 0.0248
Hs 578T GSK1059615
3.33
uM
LJP6
 72
hr
 658 860 3846 0.2237 0.0634
Hs 578T GSK1904529A
3.33
uM
LJP6
 72
hr
 658 3667 3846 0.9536 0.9440
Hs 578T GSK 690693
3.33
uM
LJP5
 72
hr
 658 3296 3846 0.8570 0.8274
Hs 578T GW843682X
3.33
uM
LJP6
 72
hr
 658 503 3846 0.1309 -0.0486
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 658 3556 3846 0.9247 0.9092
Hs 578T Sigma A6730
0.04
uM
LJP5
 72
hr
 658 3785 3846 0.9842 0.9809
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 658 2831 3846 0.7361 0.6816
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 658 3192 3846 0.8299 0.7948
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 658 1200 3846 0.3120 0.1700
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 658 1041 3846 0.2707 0.1201
Hs 578T BI-2536
0.04
uM
LJP6
 72
hr
 658 471 3846 0.1226 -0.0585
Hs 578T BMS345541
0.04
uM
LJP6
 72
hr
 658 3909 3846 1.0164 1.0198
Hs 578T SB590885
0.04
uM
LJP5
 72
hr
 658 4370 3846 1.1363 1.1644
Hs 578T PIK-93
0.04
uM
LJP5
 72
hr
 658 4012 3846 1.0433 1.0522
Hs 578T Alpelisib
0.04
uM
LJP5
 72
hr
 658 3835 3846 0.9971 0.9965
Hs 578T Luminespib
0.04
uM
LJP5
 72
hr
 658 771 3846 0.2006 0.0355
Hs 578T XMD11-85h
0.04
uM
LJP6
 72
hr
 658 3506 3846 0.9116 0.8933
Hs 578T Linsitinib
3.33
uM
LJP5
 72
hr
 658 3644 3846 0.9475 0.9366
Hs 578T Linifanib
3.33
uM
LJP6
 72
hr
 658 3493 3846 0.9084 0.8894