LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Dasatinib
0.04
uM
LJP5
 72
hr
 658 2521 3846 0.6555 0.5843
Hs 578T Dovitinib
0.04
uM
LJP5
 72
hr
 658 3188 3846 0.8290 0.7937
Hs 578T Enzastaurin
0.04
uM
LJP5
 72
hr
 658 4173 3846 1.0852 1.1027
Hs 578T Pictilisib
0.04
uM
LJP6
 72
hr
 658 2954 3846 0.7681 0.7202
Hs 578T Gefitinib
0.04
uM
LJP6
 72
hr
 658 3776 3846 0.9819 0.9782
Hs 578T Geldanamycin
0.04
uM
LJP6
 72
hr
 658 2259 3846 0.5874 0.5022
Hs 578T GSK1059615
0.04
uM
LJP5
 72
hr
 658 3932 3846 1.0225 1.0271
Hs 578T Omipalisib
0.04
uM
LJP6
 72
hr
 658 1169 3846 0.3040 0.1603
Hs 578T GSK 690693
0.04
uM
LJP5
 72
hr
 658 3424 3846 0.8903 0.8677
Hs 578T HG-5-113-01
0.04
uM
LJP5
 72
hr
 658 3655 3846 0.9504 0.9402
Hs 578T HG-5-88-01
0.04
uM
LJP6
 72
hr
 658 3417 3846 0.8884 0.8654
Hs 578T Linifanib
0.04
uM
LJP6
 72
hr
 658 3770 3846 0.9802 0.9761
Hs 578T Linsitinib
0.04
uM
LJP5
 72
hr
 658 3634 3846 0.9450 0.9337
Hs 578T Mitoxantrone
0.04
uM
LJP6
 72
hr
 658 605 3846 0.1575 -0.0165
Hs 578T MK2206
0.04
uM
LJP6
 72
hr
 658 3276 3846 0.8519 0.8213
Hs 578T Nintedanib
0.04
uM
LJP6
 72
hr
 658 3556 3846 0.9246 0.9090
Hs 578T NU7441
0.04
uM
LJP5
 72
hr
 658 3759 3846 0.9774 0.9728
Hs 578T NVP-TAE684
0.04
uM
LJP6
 72
hr
 658 3080 3846 0.8008 0.7597
Hs 578T Palbociclib
0.04
uM
LJP6
 72
hr
 658 2361 3846 0.6140 0.5343
Hs 578T PD184352
0.04
uM
LJP5
 72
hr
 658 3334 3846 0.8669 0.8395
Hs 578T Pelitinib
0.04
uM
LJP5
 72
hr
 658 3894 3846 1.0125 1.0150
Hs 578T PF477736
0.04
uM
LJP5
 72
hr
 658 3621 3846 0.9416 0.9295
Hs 578T PF562271
0.04
uM
LJP6
 72
hr
 658 3389 3846 0.8813 0.8568
Hs 578T Nilotinib
0.37
uM
LJP5
 72
hr
 658 3952 3846 1.0276 1.0333
Hs 578T Neratinib
0.37
uM
LJP5
 72
hr
 658 2043 3846 0.5312 0.4344