LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T CGP60474
0.37
uM
LJP5
 72
hr
 658 456 3846 0.1186 -0.0634
Hs 578T CGP60474
0.37
uM
LJP6
 72
hr
 658 517 3846 0.1344 -0.0443
Hs 578T CP724714
0.37
uM
LJP5
 72
hr
 658 3682 3846 0.9573 0.9485
Hs 578T CP466722
0.37
uM
LJP5
 72
hr
 658 3992 3846 1.0381 1.0460
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 658 3556 3846 0.9247 0.9092
Hs 578T Sigma A6730
0.04
uM
LJP5
 72
hr
 658 3785 3846 0.9842 0.9809
Hs 578T AT-7519
0.04
uM
LJP6
 72
hr
 658 2831 3846 0.7361 0.6816
Hs 578T AZD 5438
0.04
uM
LJP6
 72
hr
 658 3192 3846 0.8299 0.7948
Hs 578T AZD8055
0.04
uM
LJP6
 72
hr
 658 1200 3846 0.3120 0.1700
Hs 578T AZD8330
0.04
uM
LJP5
 72
hr
 658 1041 3846 0.2707 0.1201
Hs 578T BI-2536
0.04
uM
LJP6
 72
hr
 658 471 3846 0.1226 -0.0585
Hs 578T BMS345541
0.04
uM
LJP6
 72
hr
 658 3909 3846 1.0164 1.0198
Hs 578T SB590885
0.04
uM
LJP5
 72
hr
 658 4370 3846 1.1363 1.1644
Hs 578T PIK-93
0.04
uM
LJP5
 72
hr
 658 4012 3846 1.0433 1.0522
Hs 578T Alpelisib
0.04
uM
LJP5
 72
hr
 658 3835 3846 0.9971 0.9965
Hs 578T Luminespib
0.04
uM
LJP5
 72
hr
 658 771 3846 0.2006 0.0355
Hs 578T XMD11-85h
0.04
uM
LJP6
 72
hr
 658 3506 3846 0.9116 0.8933
Hs 578T HG-6-64-01
0.04
uM
LJP6
 72
hr
 658 3284 3846 0.8540 0.8239
Hs 578T WZ-4-145
0.04
uM
LJP6
 72
hr
 658 2421 3846 0.6295 0.5530
Hs 578T XMD16-144
0.04
uM
LJP5
 72
hr
 658 797 3846 0.2074 0.0438
Hs 578T Celastrol
0.04
uM
LJP6
 72
hr
 658 3892 3846 1.0119 1.0144
Hs 578T CGP60474
0.04
uM
LJP5
 72
hr
 658 2861 3846 0.7439 0.6910
Hs 578T CHIR-99021
0.04
uM
LJP6
 72
hr
 658 3568 3846 0.9279 0.9130
Hs 578T Foretinib
0.37
uM
LJP5
 72
hr
 658 1285 3846 0.3343 0.1968
Hs 578T Erlotinib
0.37
uM
LJP5
 72
hr
 658 3756 3846 0.9766 0.9717