LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T Pelitinib
0.12
uM
LJP5
 72
hr
 658 3425 3846 0.8905 0.8679
Hs 578T PF562271
0.12
uM
LJP6
 72
hr
 658 3098 3846 0.8056 0.7654
Hs 578T PHA-665752
0.12
uM
LJP5
 72
hr
 658 3930 3846 1.0220 1.0265
Hs 578T PI103
0.12
uM
LJP6
 72
hr
 658 1774 3846 0.4614 0.3502
Hs 578T PLX-4720
0.12
uM
LJP5
 72
hr
 658 4140 3846 1.0766 1.0924
Hs 578T Radicicol
0.12
uM
LJP6
 72
hr
 658 3029 3846 0.7876 0.7437
Hs 578T Seliciclib
0.12
uM
LJP5
 72
hr
 658 3900 3846 1.0141 1.0170
Hs 578T XL147
0.12
uM
LJP5
 72
hr
 658 3947 3846 1.0262 1.0316
Hs 578T Saracatinib
0.12
uM
LJP6
 72
hr
 658 3378 3846 0.8784 0.8533
Hs 578T Sorafenib
0.12
uM
LJP6
 72
hr
 658 4138 3846 1.0760 1.0917
Hs 578T SU11274
0.12
uM
LJP5
 72
hr
 658 3851 3846 1.0014 1.0016
Hs 578T TGX221
0.12
uM
LJP5
 72
hr
 658 3595 3846 0.9347 0.9212
Hs 578T Torin1
0.12
uM
LJP6
 72
hr
 658 1178 3846 0.3063 0.1631
Hs 578T Vemurafenib
0.12
uM
LJP5
 72
hr
 658 4031 3846 1.0482 1.0581
Hs 578T Withaferin A
0.12
uM
LJP5
 72
hr
 658 4079 3846 1.0606 1.0731
Hs 578T WYE-125132
0.12
uM
LJP6
 72
hr
 658 1198 3846 0.3115 0.1693
Hs 578T WZ3105
0.12
uM
LJP5
 72
hr
 658 431 3846 0.1122 -0.0711
Hs 578T YM 201636
0.12
uM
LJP5
 72
hr
 658 3853 3846 1.0019 1.0023
Hs 578T ZSTK474
0.12
uM
LJP6
 72
hr
 658 2500 3846 0.6500 0.5778
Hs 578T Sigma A6730
0.37
uM
LJP5
 72
hr
 658 3572 3846 0.9288 0.9141
Hs 578T Alvocidib
0.37
uM
LJP6
 72
hr
 658 372 3846 0.0967 -0.0898
Hs 578T AZD7762
0.37
uM
LJP6
 72
hr
 658 632 3846 0.1645 -0.0080
Hs 578T AZD8055
0.37
uM
LJP6
 72
hr
 658 939 3846 0.2442 0.0882
Hs 578T Luminespib
0.37
uM
LJP5
 72
hr
 658 769 3846 0.2000 0.0349
Hs 578T Alpelisib
0.37
uM
LJP5
 72
hr
 658 3351 3846 0.8714 0.8449