LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A JW-7-24-1
1.11
uM
LJP6
 72
hr
 962 8711 10605 0.8214 0.8036
MCF 10A Vemurafenib
3.33
uM
LJP5
 72
hr
 962 8735 10605 0.8237 0.8061
MCF 10A GSK 690693
0.37
uM
LJP5
 72
hr
 962 8775 10605 0.8274 0.8102
MCF 10A Momelotinib
0.37
uM
LJP5
 72
hr
 962 8778 10605 0.8278 0.8106
MCF 10A XL147
1.11
uM
LJP5
 72
hr
 962 8797 10605 0.8295 0.8125
MCF 10A GSK1904529A
0.12
uM
LJP6
 72
hr
 962 8802 10605 0.8300 0.8131
MCF 10A NVP-AEW541
3.33
uM
LJP5
 72
hr
 962 8808 10605 0.8306 0.8137
MCF 10A CHIR-99021
10.0
uM
LJP6
 72
hr
 962 8827 10605 0.8323 0.8156
MCF 10A Y39983
3.33
uM
LJP6
 72
hr
 962 8878 10605 0.8372 0.8209
MCF 10A SB590885
0.12
uM
LJP5
 72
hr
 962 8893 10605 0.8386 0.8225
MCF 10A BMS345541
10.0
uM
LJP6
 72
hr
 962 8900 10605 0.8392 0.8232
MCF 10A Fedratinib
0.37
uM
LJP5
 72
hr
 962 8912 10605 0.8404 0.8245
MCF 10A Seliciclib
3.33
uM
LJP5
 72
hr
 962 8937 10605 0.8427 0.8270
MCF 10A PLX-4720
10.0
uM
LJP5
 72
hr
 962 8942 10605 0.8432 0.8276
MCF 10A Dasatinib
0.04
uM
LJP5
 72
hr
 962 8953 10605 0.8442 0.8287
MCF 10A SB590885
0.04
uM
LJP5
 72
hr
 962 8969 10605 0.8458 0.8304
MCF 10A Sirolimus
10.0
uM
LJP6
 72
hr
 962 9031 10605 0.8516 0.8368
MCF 10A Linsitinib
3.33
uM
LJP5
 72
hr
 962 9064 10605 0.8547 0.8402
MCF 10A R406
1.11
uM
LJP6
 72
hr
 962 9076 10605 0.8558 0.8414
MCF 10A Crizotinib
1.11
uM
LJP5
 72
hr
 962 9096 10605 0.8578 0.8436
MCF 10A GSK1904529A
0.04
uM
LJP6
 72
hr
 962 9104 10605 0.8585 0.8444
MCF 10A SU11274
0.37
uM
LJP5
 72
hr
 962 9108 10605 0.8589 0.8448
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 962 9117 10605 0.8597 0.8457
MCF 10A Sorafenib
3.33
uM
LJP6
 72
hr
 962 9121 10605 0.8601 0.8461
MCF 10A Alpelisib
1.11
uM
LJP5
 72
hr
 962 9137 10605 0.8616 0.8478