LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | CGP60474 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 568 | 4093 | 0.1389 | -0.2224 |
| MCF7 | HG-5-113-01 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 569 | 4093 | 0.1392 | -0.2219 |
| Hs 578T | PF431396 | 10.0 | uM | LJP5 | 72 | hr | 658 | 570 | 3846 | 0.1482 | -0.0277 |
| MCF7 | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 1209 | 571 | 4093 | 0.1396 | -0.2213 |
| Hs 578T | BX-912 | 10.0 | uM | LJP5 | 72 | hr | 658 | 572 | 3846 | 0.1488 | -0.0269 |
| MCF7 | WZ3105 | 0.04 | uM | LJP5 | 72 | hr | 1209 | 572 | 4093 | 0.1398 | -0.2211 |
| Hs 578T | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 658 | 573 | 3846 | 0.1490 | -0.0267 |
| Hs 578T | PF477736 | 1.11 | uM | LJP5 | 72 | hr | 658 | 574 | 3846 | 0.1492 | -0.0264 |
| MCF 10A | Withaferin A | 10.0 | uM | LJP6 | 72 | hr | 962 | 574 | 10605 | 0.0541 | -0.0403 |
| MDA-MB-231 | Momelotinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 574 | 4513 | 0.1272 | -0.2019 |
| Hs 578T | Dasatinib | 1.11 | uM | LJP6 | 72 | hr | 658 | 574 | 3846 | 0.1494 | -0.0262 |
| Hs 578T | PHA-793887 | 1.11 | uM | LJP6 | 72 | hr | 658 | 576 | 3846 | 0.1499 | -0.0256 |
| Hs 578T | HG-6-64-01 | 3.33 | uM | LJP6 | 72 | hr | 658 | 576 | 3846 | 0.1499 | -0.0256 |
| Hs 578T | BI-2536 | 1.11 | uM | LJP6 | 72 | hr | 658 | 578 | 3846 | 0.1504 | -0.0250 |
| Hs 578T | QL-XII-47 | 10.0 | uM | LJP6 | 72 | hr | 658 | 578 | 3846 | 0.1503 | -0.0252 |
| Hs 578T | Withaferin A | 3.33 | uM | LJP5 | 72 | hr | 658 | 581 | 3846 | 0.1512 | -0.0241 |
| Hs 578T | HG-5-113-01 | 10.0 | uM | LJP5 | 72 | hr | 658 | 581 | 3846 | 0.1512 | -0.0240 |
| Hs 578T | Withaferin A | 3.33 | uM | LJP6 | 72 | hr | 658 | 583 | 3846 | 0.1516 | -0.0236 |
| BT-20 | Alvocidib | 10.0 | uM | LJP6 | 72 | hr | 1097 | 586 | 3769 | 0.1555 | -0.1913 |
| MCF 10A | Buparlisib | 10.0 | uM | LJP5 | 72 | hr | 962 | 586 | 10605 | 0.0553 | -0.0390 |
| MCF 10A | QL-X-138 | 10.0 | uM | LJP6 | 72 | hr | 962 | 587 | 10605 | 0.0554 | -0.0389 |
| Hs 578T | Geldanamycin | 10.0 | uM | LJP5 | 72 | hr | 658 | 588 | 3846 | 0.1530 | -0.0219 |
| BT-20 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1097 | 588 | 3769 | 0.1560 | -0.1906 |
| MDA-MB-231 | SNS-032 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 590 | 4513 | 0.1308 | -0.1970 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 591 | 4093 | 0.1445 | -0.2144 |