LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 CGP60474
1.11
uM
LJP6
 72
hr
 1097 538 3769 0.1427 -0.2093
Hs 578T Dasatinib
3.33
uM
LJP6
 72
hr
 658 540 3846 0.1405 -0.0370
BT-20 AZD 5438
10.0
uM
LJP6
 72
hr
 1097 540 3769 0.1433 -0.2085
BT-20 AT-7519
3.33
uM
LJP6
 72
hr
 1097 540 3769 0.1433 -0.2085
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 72
hr
 1235 541 4513 0.1200 -0.2118
MDA-MB-231 JNK-9L
10.0
uM
LJP6
 72
hr
 1235 541 4513 0.1200 -0.2118
Hs 578T SNS-032
0.12
uM
LJP6
 72
hr
 658 542 3846 0.1411 -0.0362
Hs 578T SNS-032
1.11
uM
LJP6
 72
hr
 658 548 3846 0.1425 -0.0346
MCF 10A Mitoxantrone
10.0
uM
LJP6
 72
hr
 962 552 10605 0.0521 -0.0425
MDA-MB-231 WZ-4-145
10.0
uM
LJP6
 72
hr
 1235 552 4513 0.1224 -0.2086
MDA-MB-231 SNS-032
0.12
uM
LJP6
 72
hr
 1235 554 4513 0.1227 -0.2081
Hs 578T Torin2
1.11
uM
LJP5
 72
hr
 658 554 3846 0.1440 -0.0327
Hs 578T Dasatinib
3.33
uM
LJP5
 72
hr
 658 556 3846 0.1447 -0.0320
SK-BR-3 LDN-193189
10.0
uM
LJP5
 72
hr
 1401 557 4223 0.1319 -0.2993
Hs 578T Momelotinib
10.0
uM
LJP5
 72
hr
 658 561 3846 0.1459 -0.0305
Hs 578T AZD 5438
1.11
uM
LJP6
 72
hr
 658 562 3846 0.1462 -0.0301
MDA-MB-231 AZD8055
10.0
uM
LJP6
 72
hr
 1235 562 4513 0.1246 -0.2055
MCF7 CGP60474
0.37
uM
LJP5
 72
hr
 1209 566 4093 0.1384 -0.2231
Hs 578T PF477736
3.33
uM
LJP5
 72
hr
 658 566 3846 0.1473 -0.0288
BT-20 Withaferin A
10.0
uM
LJP6
 72
hr
 1097 566 3769 0.1502 -0.1987
Hs 578T Y39983
10.0
uM
LJP6
 72
hr
 658 567 3846 0.1476 -0.0284
Hs 578T Dasatinib
1.11
uM
LJP5
 72
hr
 658 567 3846 0.1475 -0.0285
Hs 578T Neratinib
10.0
uM
LJP5
 72
hr
 658 568 3846 0.1479 -0.0281
BT-20 Withaferin A
3.33
uM
LJP5
 72
hr
 1097 568 3769 0.1509 -0.1978
MCF7 CGP60474
10.0
uM
LJP5
 72
hr
 1209 568 4093 0.1389 -0.2224