LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | CGP60474 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 292 | 4513 | 0.0647 | -0.2880 |
| BT-20 | Celastrol | 10.0 | uM | LJP6 | 72 | hr | 1097 | 333 | 3769 | 0.0883 | -0.2860 |
| MCF7 | AZD8055 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 388 | 4093 | 0.0949 | -0.2848 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 403 | 4093 | 0.0985 | -0.2797 |
| MDA-MB-231 | AT-7519 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 324 | 4513 | 0.0719 | -0.2780 |
| BT-20 | GSK1059615 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 354 | 3769 | 0.0941 | -0.2779 |
| MCF7 | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 409 | 4093 | 0.0999 | -0.2776 |
| BT-20 | LDN-193189 | 3.33 | uM | LJP5 | 72 | hr | 1097 | 357 | 3769 | 0.0947 | -0.2770 |
| MDA-MB-231 | Geldanamycin | 10.0 | uM | LJP6 | 72 | hr | 1235 | 334 | 4513 | 0.0741 | -0.2751 |
| MDA-MB-231 | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 340 | 4513 | 0.0755 | -0.2732 |
| MDA-MB-231 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 344 | 4513 | 0.0762 | -0.2721 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1235 | 344 | 4513 | 0.0762 | -0.2721 |
| MCF7 | YM 201636 | 10.0 | uM | LJP5 | 72 | hr | 1209 | 435 | 4093 | 0.1064 | -0.2684 |
| MDA-MB-231 | LDN-193189 | 3.33 | uM | LJP5 | 72 | hr | 1235 | 357 | 4513 | 0.0791 | -0.2682 |
| MDA-MB-231 | AZD 5438 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 361 | 4513 | 0.0800 | -0.2669 |
| MCF7 | AT-7519 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 443 | 4093 | 0.1084 | -0.2656 |
| MDA-MB-231 | NVP-TAE684 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 382 | 4513 | 0.0848 | -0.2603 |
| MCF7 | JNK-9L | 1.11 | uM | LJP6 | 72 | hr | 1209 | 460 | 4093 | 0.1125 | -0.2598 |
| MDA-MB-231 | Fedratinib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 398 | 4513 | 0.0882 | -0.2557 |
| MDA-MB-231 | PHA-793887 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 398 | 4513 | 0.0883 | -0.2556 |
| MCF7 | CGP60474 | 10.0 | uM | LJP6 | 72 | hr | 1209 | 474 | 4093 | 0.1160 | -0.2549 |
| MDA-MB-231 | Y39983 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 403 | 4513 | 0.0893 | -0.2541 |
| MDA-MB-231 | CGP60474 | 1.11 | uM | LJP5 | 72 | hr | 1235 | 407 | 4513 | 0.0902 | -0.2528 |
| MDA-MB-231 | BMS345541 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 408 | 4513 | 0.0905 | -0.2524 |
| MDA-MB-231 | AZD7762 | 10.0 | uM | LJP6 | 72 | hr | 1235 | 409 | 4513 | 0.0907 | -0.2522 |