LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | SNS-032 | 1.11 | uM | LJP6 | 72 | hr | 1209 | 720 | 4093 | 0.1759 | -0.1698 |
| SK-BR-3 | Radicicol | 10.0 | uM | LJP6 | 72 | hr | 1401 | 922 | 4223 | 0.2185 | -0.1697 |
| BT-20 | Torin2 | 1.11 | uM | LJP5 | 72 | hr | 1097 | 644 | 3769 | 0.1708 | -0.1696 |
| BT-20 | Torin2 | 3.33 | uM | LJP5 | 72 | hr | 1097 | 644 | 3769 | 0.1708 | -0.1696 |
| SK-BR-3 | Omipalisib | 3.33 | uM | LJP6 | 72 | hr | 1401 | 924 | 4223 | 0.2188 | -0.1692 |
| MCF7 | SNS-032 | 0.37 | uM | LJP6 | 72 | hr | 1209 | 723 | 4093 | 0.1766 | -0.1687 |
| MDA-MB-231 | JNK-9L | 3.33 | uM | LJP6 | 72 | hr | 1235 | 687 | 4513 | 0.1524 | -0.1673 |
| Hs 578T | SB590885 | 10.0 | uM | LJP5 | 72 | hr | 658 | 125 | 3846 | 0.0327 | -0.1670 |
| SK-BR-3 | A443654 | 10.0 | uM | LJP6 | 72 | hr | 1401 | 931 | 4223 | 0.2206 | -0.1665 |
| SK-BR-3 | Withaferin A | 3.33 | uM | LJP5 | 72 | hr | 1401 | 931 | 4223 | 0.2206 | -0.1665 |
| MDA-MB-231 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1235 | 690 | 4513 | 0.1529 | -0.1665 |
| MDA-MB-231 | Mitoxantrone | 0.37 | uM | LJP6 | 72 | hr | 1235 | 692 | 4513 | 0.1533 | -0.1660 |
| SK-BR-3 | CGP60474 | 1.11 | uM | LJP6 | 72 | hr | 1401 | 934 | 4223 | 0.2213 | -0.1655 |
| BT-20 | Torin2 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 656 | 3769 | 0.1740 | -0.1651 |
| MCF7 | SNS-032 | 0.12 | uM | LJP6 | 72 | hr | 1209 | 734 | 4093 | 0.1795 | -0.1647 |
| BT-20 | Mitoxantrone | 3.33 | uM | LJP6 | 72 | hr | 1097 | 657 | 3769 | 0.1745 | -0.1645 |
| MDA-MB-231 | Luminespib | 10.0 | uM | LJP5 | 72 | hr | 1235 | 696 | 4513 | 0.1544 | -0.1645 |
| MDA-MB-231 | XMD16-144 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 699 | 4513 | 0.1550 | -0.1636 |
| BT-20 | WZ3105 | 10.0 | uM | LJP5 | 72 | hr | 1097 | 661 | 3769 | 0.1754 | -0.1631 |
| MDA-MB-231 | WZ3105 | 10.0 | uM | LJP5 | 72 | hr | 1235 | 702 | 4513 | 0.1556 | -0.1628 |
| BT-20 | CGP60474 | 0.12 | uM | LJP6 | 72 | hr | 1097 | 663 | 3769 | 0.1760 | -0.1624 |
| SK-BR-3 | WZ3105 | 1.11 | uM | LJP5 | 72 | hr | 1401 | 945 | 4223 | 0.2239 | -0.1617 |
| MCF7 | Withaferin A | 10.0 | uM | LJP5 | 72 | hr | 1209 | 744 | 4093 | 0.1818 | -0.1615 |
| MCF7 | Foretinib | 10.0 | uM | LJP5 | 72 | hr | 1209 | 745 | 4093 | 0.1820 | -0.1611 |
| MCF7 | PHA-793887 | 3.33 | uM | LJP6 | 72 | hr | 1209 | 745 | 4093 | 0.1821 | -0.1610 |