LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A CGP60474
0.04
uM
LJP6
 72
hr
 962 400 10605 0.0378 -0.0582
Hs 578T Mitoxantrone
3.33
uM
LJP6
 72
hr
 658 147 3846 0.0384 -0.1601
MCF 10A PF431396
10.0
uM
LJP5
 72
hr
 962 413 10605 0.0389 -0.0570
MCF 10A AZD7762
10.0
uM
LJP6
 72
hr
 962 414 10605 0.0391 -0.0568
Hs 578T Mitoxantrone
3.33
uM
LJP5
 72
hr
 658 154 3846 0.0401 -0.1581
MDA-MB-231 Mitoxantrone
3.33
uM
LJP5
 72
hr
 1235 185 4513 0.0411 -0.3204
MCF7 HG-6-64-01
10.0
uM
LJP6
 72
hr
 1209 170 4093 0.0415 -0.3605
BT-20 Mitoxantrone
10.0
uM
LJP5
 72
hr
 1097 158 3769 0.0419 -0.3515
MCF 10A SNS-032
0.37
uM
LJP6
 72
hr
 962 452 10605 0.0426 -0.0529
MCF 10A JNK-9L
3.33
uM
LJP6
 72
hr
 962 460 10605 0.0434 -0.0520
MCF 10A Mitoxantrone
3.33
uM
LJP6
 72
hr
 962 460 10605 0.0434 -0.0520
MCF 10A GSK1059615
10.0
uM
LJP5
 72
hr
 962 480 10605 0.0453 -0.0500
MDA-MB-231 Mitoxantrone
3.33
uM
LJP6
 72
hr
 1235 205 4513 0.0455 -0.3144
MCF 10A GSK1059615
10.0
uM
LJP6
 72
hr
 962 491 10605 0.0464 -0.0488
MCF 10A Radicicol
10.0
uM
LJP5
 72
hr
 962 495 10605 0.0467 -0.0484
Hs 578T LDN-193189
3.33
uM
LJP5
 72
hr
 658 183 3846 0.0476 -0.1491
MCF 10A Mitoxantrone
10.0
uM
LJP5
 72
hr
 962 509 10605 0.0480 -0.0470
Hs 578T HG-6-64-01
10.0
uM
LJP6
 72
hr
 658 184 3846 0.0480 -0.1485
Hs 578T WH-4-025
10.0
uM
LJP5
 72
hr
 658 186 3846 0.0484 -0.1481
MCF 10A Dasatinib
10.0
uM
LJP6
 72
hr
 962 514 10605 0.0485 -0.0464
MCF 10A QL-XII-47
10.0
uM
LJP6
 72
hr
 962 522 10605 0.0492 -0.0456
MCF 10A WZ3105
0.37
uM
LJP5
 72
hr
 962 522 10605 0.0493 -0.0456
MDA-MB-231 HG-6-64-01
10.0
uM
LJP6
 72
hr
 1235 234 4513 0.0518 -0.3057
MCF 10A Mitoxantrone
10.0
uM
LJP6
 72
hr
 962 552 10605 0.0521 -0.0425
Hs 578T AZD7762
10.0
uM
LJP6
 72
hr
 658 203 3846 0.0530 -0.1426