LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
Hs 578T WZ3105
0.04
uM
LJP5
 72
hr
 658 454 3846 0.1180 -0.0641
Hs 578T WZ3105
10.0
uM
LJP5
 72
hr
 658 454 3846 0.1180 -0.0641
MCF 10A PF562271
3.33
uM
LJP6
 72
hr
 962 1254 10605 0.1182 0.0303
MDA-MB-231 CGP60474
0.04
uM
LJP6
 72
hr
 1235 534 4513 0.1183 -0.2142
MCF 10A GDC-0980
3.33
uM
LJP5
 72
hr
 962 1254 10605 0.1183 0.0303
MDA-MB-231 Torin2
10.0
uM
LJP5
 72
hr
 1235 534 4513 0.1184 -0.2141
Hs 578T BI-2536
10.0
uM
LJP6
 72
hr
 658 455 3846 0.1184 -0.0636
Hs 578T CGP60474
0.37
uM
LJP5
 72
hr
 658 456 3846 0.1186 -0.0634
Hs 578T Afatinib
10.0
uM
LJP6
 72
hr
 658 457 3846 0.1188 -0.0631
Hs 578T PHA-793887
10.0
uM
LJP6
 72
hr
 658 457 3846 0.1190 -0.0629
MCF 10A Torin1
10.0
uM
LJP6
 72
hr
 962 1262 10605 0.1190 0.0311
MCF 10A Gefitinib
10.0
uM
LJP6
 72
hr
 962 1262 10605 0.1191 0.0312
MCF 10A XMD16-144
3.33
uM
LJP5
 72
hr
 962 1265 10605 0.1193 0.0314
MCF 10A Tozasertib
10.0
uM
LJP5
 72
hr
 962 1266 10605 0.1194 0.0316
Hs 578T Torin1
10.0
uM
LJP6
 72
hr
 658 459 3846 0.1195 -0.0623
Hs 578T WH-4-025
3.33
uM
LJP5
 72
hr
 658 460 3846 0.1196 -0.0622
MCF 10A Dasatinib
1.11
uM
LJP6
 72
hr
 962 1272 10605 0.1200 0.0322
Hs 578T CGP60474
1.11
uM
LJP6
 72
hr
 658 461 3846 0.1200 -0.0616
MDA-MB-231 JNK-9L
10.0
uM
LJP6
 72
hr
 1235 541 4513 0.1200 -0.2118
MDA-MB-231 Geldanamycin
10.0
uM
LJP5
 72
hr
 1235 541 4513 0.1200 -0.2118
MCF7 A443654
0.37
uM
LJP6
 72
hr
 1209 491 4093 0.1200 -0.2492
MCF 10A PF431396
1.11
uM
LJP5
 72
hr
 962 1275 10605 0.1203 0.0325
MCF 10A Dasatinib
3.33
uM
LJP5
 72
hr
 962 1276 10605 0.1204 0.0326
MCF 10A Torin2
10.0
uM
LJP5
 72
hr
 962 1277 10605 0.1204 0.0327
BT-20 GSK1059615
10.0
uM
LJP6
 72
hr
 1097 454 3769 0.1206 -0.2405