LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 CGP60474
10.0
uM
LJP6
 72
hr
 1097 427 3769 0.1135 -0.2506
Hs 578T Omipalisib
3.33
uM
LJP6
 72
hr
 658 436 3846 0.1135 -0.0696
MCF 10A SNS-032
0.12
uM
LJP6
 72
hr
 962 1209 10605 0.1140 0.0256
Hs 578T CGP60474
3.33
uM
LJP6
 72
hr
 658 440 3846 0.1144 -0.0684
MDA-MB-231 Alvocidib
0.12
uM
LJP6
 72
hr
 1235 517 4513 0.1145 -0.2194
MDA-MB-231 GSK1059615
10.0
uM
LJP5
 72
hr
 1235 518 4513 0.1148 -0.2190
MDA-MB-231 WZ3105
3.33
uM
LJP5
 72
hr
 1235 518 4513 0.1148 -0.2189
Hs 578T AT-7519
1.11
uM
LJP6
 72
hr
 658 442 3846 0.1149 -0.0678
SK-BR-3 AT-7519
10.0
uM
LJP6
 72
hr
 1401 486 4223 0.1151 -0.3245
MCF 10A PHA-793887
0.37
uM
LJP6
 72
hr
 962 1224 10605 0.1154 0.0272
MDA-MB-231 CGP60474
0.37
uM
LJP5
 72
hr
 1235 521 4513 0.1154 -0.2181
MCF 10A Afatinib
10.0
uM
LJP6
 72
hr
 962 1227 10605 0.1157 0.0275
MDA-MB-231 LDN-193189
10.0
uM
LJP5
 72
hr
 1235 522 4513 0.1157 -0.2178
MCF 10A Geldanamycin
0.04
uM
LJP6
 72
hr
 962 1229 10605 0.1159 0.0277
MCF7 CGP60474
10.0
uM
LJP6
 72
hr
 1209 474 4093 0.1160 -0.2549
Hs 578T AZD 5438
3.33
uM
LJP6
 72
hr
 658 446 3846 0.1161 -0.0664
BT-20 A443654
10.0
uM
LJP6
 72
hr
 1097 437 3769 0.1161 -0.2468
Hs 578T Torin2
10.0
uM
LJP5
 72
hr
 658 447 3846 0.1164 -0.0660
MDA-MB-231 A443654
1.11
uM
LJP6
 72
hr
 1235 525 4513 0.1164 -0.2168
MDA-MB-231 SNS-032
1.11
uM
LJP6
 72
hr
 1235 525 4513 0.1165 -0.2167
Hs 578T Pelitinib
10.0
uM
LJP5
 72
hr
 658 448 3846 0.1167 -0.0657
Hs 578T PF477736
10.0
uM
LJP5
 72
hr
 658 449 3846 0.1169 -0.0654
MDA-MB-231 SNS-032
3.33
uM
LJP6
 72
hr
 1235 530 4513 0.1174 -0.2154
MCF 10A TWS119
10.0
uM
LJP5
 72
hr
 962 1247 10605 0.1176 0.0296
MCF 10A Momelotinib
10.0
uM
LJP5
 72
hr
 962 1247 10605 0.1177 0.0296