LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Torin2
0.04
uM
LJP5
 72
hr
 962 1127 10605 0.1063 0.0172
Hs 578T Alvocidib
0.12
uM
LJP6
 72
hr
 658 409 3846 0.1064 -0.0781
MCF7 YM 201636
10.0
uM
LJP5
 72
hr
 1209 435 4093 0.1064 -0.2684
MCF 10A PD0325901
3.33
uM
LJP6
 72
hr
 962 1133 10605 0.1069 0.0178
MCF 10A PD0325901
10.0
uM
LJP6
 72
hr
 962 1137 10605 0.1072 0.0181
MCF 10A Dovitinib
3.33
uM
LJP5
 72
hr
 962 1141 10605 0.1076 0.0186
MDA-MB-231 SNS-032
0.37
uM
LJP6
 72
hr
 1235 489 4513 0.1083 -0.2279
MCF7 AT-7519
10.0
uM
LJP6
 72
hr
 1209 443 4093 0.1084 -0.2656
Hs 578T Alvocidib
3.33
uM
LJP6
 72
hr
 658 419 3846 0.1090 -0.0749
MCF 10A BX-912
10.0
uM
LJP5
 72
hr
 962 1162 10605 0.1096 0.0207
MDA-MB-231 AT-7519
0.37
uM
LJP6
 72
hr
 1235 496 4513 0.1100 -0.2257
Hs 578T AT-7519
0.37
uM
LJP6
 72
hr
 658 423 3846 0.1102 -0.0736
MDA-MB-231 AZD7762
3.33
uM
LJP6
 72
hr
 1235 497 4513 0.1102 -0.2254
Hs 578T Alvocidib
1.11
uM
LJP6
 72
hr
 658 424 3846 0.1102 -0.0735
MDA-MB-231 WZ3105
0.04
uM
LJP5
 72
hr
 1235 498 4513 0.1103 -0.2251
Hs 578T Geldanamycin
10.0
uM
LJP6
 72
hr
 658 425 3846 0.1105 -0.0731
MDA-MB-231 CGP60474
0.12
uM
LJP6
 72
hr
 1235 506 4513 0.1121 -0.2227
Hs 578T WZ3105
0.12
uM
LJP5
 72
hr
 658 431 3846 0.1122 -0.0711
Hs 578T Foretinib
10.0
uM
LJP5
 72
hr
 658 431 3846 0.1122 -0.0711
MDA-MB-231 Buparlisib
10.0
uM
LJP5
 72
hr
 1235 506 4513 0.1123 -0.2225
MCF7 JNK-9L
1.11
uM
LJP6
 72
hr
 1209 460 4093 0.1125 -0.2598
MCF 10A XMD11-50
10.0
uM
LJP6
 72
hr
 962 1194 10605 0.1127 0.0241
Hs 578T CGP60474
1.11
uM
LJP5
 72
hr
 658 435 3846 0.1132 -0.0699
Hs 578T Dasatinib
10.0
uM
LJP6
 72
hr
 658 436 3846 0.1134 -0.0697
Hs 578T Omipalisib
3.33
uM
LJP6
 72
hr
 658 436 3846 0.1135 -0.0696