LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Dovitinib
3.33
uM
LJP5
 72
hr
 1097 1500 3769 0.3981 0.1510
BT-20 Enzastaurin
3.33
uM
LJP5
 72
hr
 1097 4264 3769 1.1313 1.1852
BT-20 Erlotinib
3.33
uM
LJP5
 72
hr
 1097 3231 3769 0.8573 0.7987
BT-20 Foretinib
3.33
uM
LJP5
 72
hr
 1097 1303 3769 0.3458 0.0772
Hs 578T SU11274
0.37
uM
LJP5
 72
hr
 658 3698 3846 0.9616 0.9536
Hs 578T Fedratinib
0.37
uM
LJP5
 72
hr
 658 3225 3846 0.8385 0.8052
Hs 578T Tozasertib
0.37
uM
LJP5
 72
hr
 658 789 3846 0.2051 0.0410
BT-20 Geldanamycin
3.33
uM
LJP5
 72
hr
 1097 936 3769 0.2483 -0.0603
BT-20 WH-4-025
0.37
uM
LJP5
 72
hr
 1097 2814 3769 0.7467 0.6427
BT-20 GSK1059615
3.33
uM
LJP5
 72
hr
 1097 474 3769 0.1258 -0.2331
BT-20 SB590885
0.04
uM
LJP5
 72
hr
 1097 3918 3769 1.0395 1.0557
BT-20 Sigma A6730
0.04
uM
LJP5
 72
hr
 1097 3200 3769 0.8491 0.7871
BT-20 XMD16-144
0.37
uM
LJP5
 72
hr
 1097 1323 3769 0.3512 0.0847
BT-20 GSK 690693
3.33
uM
LJP5
 72
hr
 1097 2005 3769 0.5321 0.3399
BT-20 Brivanib
0.37
uM
LJP5
 72
hr
 1097 3699 3769 0.9813 0.9736
BT-20 HG-5-113-01
3.33
uM
LJP5
 72
hr
 1097 1818 3769 0.4823 0.2697
BT-20 Buparlisib
0.37
uM
LJP5
 72
hr
 1097 1950 3769 0.5175 0.3194
BT-20 NU7441
3.33
uM
LJP5
 72
hr
 1097 3048 3769 0.8086 0.7300
BT-20 BX-912
0.37
uM
LJP5
 72
hr
 1097 3616 3769 0.9594 0.9427
BT-20 Linsitinib
0.04
uM
LJP5
 72
hr
 1097 3436 3769 0.9116 0.8753
BT-20 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1097 3912 3769 1.0378 1.0533
BT-20 LDN-193189
3.33
uM
LJP5
 72
hr
 1097 357 3769 0.0947 -0.2770
BT-20 SB590885
0.12
uM
LJP5
 72
hr
 1097 3896 3769 1.0337 1.0476
BT-20 Linsitinib
3.33
uM
LJP5
 72
hr
 1097 3521 3769 0.9342 0.9072
Hs 578T AZD8330
1.11
uM
LJP5
 72
hr
 658 1003 3846 0.2608 0.1082