LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
SK-BR-3 PHA-793887
10.0
uM
LJP6
 72
hr
 1401 1099 4223 0.2603 -0.1071
SK-BR-3 PI103
10.0
uM
LJP6
 72
hr
 1401 1348 4223 0.3193 -0.0189
SK-BR-3 QL-X-138
10.0
uM
LJP6
 72
hr
 1401 1228 4223 0.2909 -0.0614
SK-BR-3 QL-XII-47
10.0
uM
LJP6
 72
hr
 1401 1099 4223 0.2604 -0.1070
SK-BR-3 Radicicol
10.0
uM
LJP6
 72
hr
 1401 922 4223 0.2185 -0.1697
SK-BR-3 Saracatinib
10.0
uM
LJP6
 72
hr
 1401 2100 4223 0.4974 0.2478
SK-BR-3 Selumetinib
10.0
uM
LJP6
 72
hr
 1401 4192 4223 0.9927 0.9891
SK-BR-3 Sirolimus
10.0
uM
LJP6
 72
hr
 1401 2532 4223 0.5997 0.4009
SK-BR-3 Sorafenib
10.0
uM
LJP6
 72
hr
 1401 2693 4223 0.6378 0.4578
SK-BR-3 Torin1
10.0
uM
LJP6
 72
hr
 1401 1306 4223 0.3094 -0.0336
SK-BR-3 Withaferin A
10.0
uM
LJP6
 72
hr
 1401 1153 4223 0.2731 -0.0880
SK-BR-3 WYE-125132
10.0
uM
LJP6
 72
hr
 1401 1467 4223 0.3474 0.0232
SK-BR-3 XMD11-50
10.0
uM
LJP6
 72
hr
 1401 1955 4223 0.4629 0.1962
SK-BR-3 Y39983
10.0
uM
LJP6
 72
hr
 1401 1540 4223 0.3647 0.0491
BT-20 Afatinib
0.04
uM
LJP6
 72
hr
 1097 2874 3769 0.7625 0.6650