LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 LDN-193189
0.04
uM
LJP5
 72
hr
 1097 3807 3769 1.0099 1.0140
BT-20 Nilotinib
3.33
uM
LJP5
 72
hr
 1097 3734 3769 0.9907 0.9868
BT-20 Dactolisib
3.33
uM
LJP5
 72
hr
 1097 1295 3769 0.3435 0.0740
BT-20 WH-4-025
0.37
uM
LJP5
 72
hr
 1097 2814 3769 0.7467 0.6427
BT-20 SB590885
0.04
uM
LJP5
 72
hr
 1097 3918 3769 1.0395 1.0557
BT-20 XMD16-144
0.37
uM
LJP5
 72
hr
 1097 1323 3769 0.3512 0.0847
BT-20 Brivanib
0.37
uM
LJP5
 72
hr
 1097 3699 3769 0.9813 0.9736
BT-20 Buparlisib
0.37
uM
LJP5
 72
hr
 1097 1950 3769 0.5175 0.3194
BT-20 BX-912
0.37
uM
LJP5
 72
hr
 1097 3616 3769 0.9594 0.9427
BT-20 NVP-AEW541
0.12
uM
LJP5
 72
hr
 1097 3912 3769 1.0378 1.0533
BT-20 SB590885
0.12
uM
LJP5
 72
hr
 1097 3896 3769 1.0337 1.0476
BT-20 CGP60474
0.37
uM
LJP5
 72
hr
 1097 716 3769 0.1900 -0.1426
BT-20 PIK-93
0.12
uM
LJP5
 72
hr
 1097 4017 3769 1.0656 1.0926
BT-20 LDN-193189
0.37
uM
LJP5
 72
hr
 1097 3201 3769 0.8493 0.7874
BT-20 CP724714
0.37
uM
LJP5
 72
hr
 1097 3643 3769 0.9665 0.9528
BT-20 CP466722
0.37
uM
LJP5
 72
hr
 1097 3786 3769 1.0044 1.0062
BT-20 Crizotinib
0.37
uM
LJP5
 72
hr
 1097 3267 3769 0.8668 0.8121
BT-20 Momelotinib
0.37
uM
LJP5
 72
hr
 1097 3474 3769 0.9216 0.8894
BT-20 Dasatinib
0.37
uM
LJP5
 72
hr
 1097 1463 3769 0.3881 0.1369
BT-20 Luminespib
0.12
uM
LJP5
 72
hr
 1097 1164 3769 0.3090 0.0252
BT-20 Dovitinib
0.37
uM
LJP5
 72
hr
 1097 1624 3769 0.4310 0.1974
BT-20 Enzastaurin
0.37
uM
LJP5
 72
hr
 1097 4103 3769 1.0886 1.1249
BT-20 Erlotinib
0.37
uM
LJP5
 72
hr
 1097 3329 3769 0.8832 0.8353
BT-20 Foretinib
0.37
uM
LJP5
 72
hr
 1097 1634 3769 0.4335 0.2009
BT-20 PLX-4720
3.33
uM
LJP5
 72
hr
 1097 2550 3769 0.6767 0.5439