LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
SK-BR-3 ZSTK474
1.11
uM
LJP6
 72
hr
 1401 1708 4223 0.4044 0.1086
MCF7 ZSTK474
3.33
uM
LJP6
 72
hr
 1209 1057 4093 0.2584 -0.0527
SK-BR-3 ZSTK474
0.04
uM
LJP6
 72
hr
 1401 3262 4223 0.7725 0.6595
Hs 578T ZSTK474
0.37
uM
LJP6
 72
hr
 658 2225 3846 0.5785 0.4915
MCF 10A ZSTK474
0.37
uM
LJP6
 72
hr
 962 7328 10605 0.6910 0.6602
BT-20 ZSTK474
3.33
uM
LJP6
 72
hr
 1097 1050 3769 0.2786 -0.0176
BT-20 ZSTK474
0.37
uM
LJP6
 72
hr
 1097 1979 3769 0.5250 0.3300
Hs 578T ZSTK474
3.33
uM
LJP6
 72
hr
 658 1511 3846 0.3930 0.2676
MCF 10A ZSTK474
0.12
uM
LJP6
 72
hr
 962 9117 10605 0.8597 0.8457
MCF 10A ZSTK474
3.33
uM
LJP6
 72
hr
 962 2212 10605 0.2086 0.1297
MCF 10A ZSTK474
10.0
uM
LJP6
 72
hr
 962 1349 10605 0.1273 0.0402
BT-20 YM 201636
10.0
uM
LJP5
 72
hr
 1097 1092 3769 0.2899 -0.0017
Hs 578T YM 201636
10.0
uM
LJP5
 72
hr
 658 821 3846 0.2135 0.0511
BT-20 YM 201636
1.11
uM
LJP5
 72
hr
 1097 2848 3769 0.7555 0.6552
MCF 10A YM 201636
1.11
uM
LJP5
 72
hr
 962 7826 10605 0.7380 0.7119
Hs 578T YM 201636
0.37
uM
LJP5
 72
hr
 658 3791 3846 0.9857 0.9827
MCF 10A YM 201636
0.37
uM
LJP5
 72
hr
 962 10078 10605 0.9503 0.9453
MDA-MB-231 YM 201636
0.04
uM
LJP5
 72
hr
 1235 4673 4513 1.0355 1.0488
MCF7 YM 201636
10.0
uM
LJP5
 72
hr
 1209 435 4093 0.1064 -0.2684
MCF7 YM 201636
3.33
uM
LJP5
 72
hr
 1209 1757 4093 0.4294 0.1900
Hs 578T YM 201636
0.04
uM
LJP5
 72
hr
 658 3968 3846 1.0319 1.0384
BT-20 YM 201636
0.04
uM
LJP5
 72
hr
 1097 4179 3769 1.1087 1.1534
MCF7 YM 201636
0.12
uM
LJP5
 72
hr
 1209 3938 4093 0.9623 0.9465
MCF7 YM 201636
0.37
uM
LJP5
 72
hr
 1209 3484 4093 0.8514 0.7890
Hs 578T YM 201636
3.33
uM
LJP5
 72
hr
 658 2502 3846 0.6505 0.5784