LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF7 XL147
1.11
uM
LJP5
 72
hr
 1209 4323 4093 1.0563 1.0799
MDA-MB-231 XL147
3.33
uM
LJP5
 72
hr
 1235 4806 4513 1.0648 1.0892
MCF7 WZ-4-145
0.12
uM
LJP6
 72
hr
 1209 2527 4093 0.6176 0.4571
BT-20 WZ-4-145
10.0
uM
LJP6
 72
hr
 1097 1200 3769 0.3185 0.0387
MCF7 WZ-4-145
3.33
uM
LJP6
 72
hr
 1209 1357 4093 0.3316 0.0513
MDA-MB-231 WZ-4-145
1.11
uM
LJP6
 72
hr
 1235 2984 4513 0.6612 0.5334
SK-BR-3 WZ-4-145
0.04
uM
LJP6
 72
hr
 1401 2442 4223 0.5783 0.3689
MCF7 WZ-4-145
0.04
uM
LJP6
 72
hr
 1209 2751 4093 0.6721 0.5346
MDA-MB-231 WZ-4-145
0.37
uM
LJP6
 72
hr
 1235 3218 4513 0.7131 0.6049
MCF7 WZ-4-145
0.37
uM
LJP6
 72
hr
 1209 2178 4093 0.5321 0.3359
MCF 10A WZ-4-145
0.37
uM
LJP6
 72
hr
 962 9478 10605 0.8938 0.8832
BT-20 WZ-4-145
0.04
uM
LJP6
 72
hr
 1097 2843 3769 0.7544 0.6535
MCF 10A WZ-4-145
1.11
uM
LJP6
 72
hr
 962 7948 10605 0.7495 0.7245
MDA-MB-231 WZ-4-145
0.12
uM
LJP6
 72
hr
 1235 3493 4513 0.7740 0.6887
MDA-MB-231 WZ-4-145
3.33
uM
LJP6
 72
hr
 1235 2486 4513 0.5508 0.3814
Hs 578T WZ-4-145
0.12
uM
LJP6
 72
hr
 658 2457 3846 0.6388 0.5643
Hs 578T WZ-4-145
0.04
uM
LJP6
 72
hr
 658 2421 3846 0.6295 0.5530
BT-20 WZ-4-145
3.33
uM
LJP6
 72
hr
 1097 2046 3769 0.5428 0.3550
Hs 578T WZ-4-145
10.0
uM
LJP6
 72
hr
 658 513 3846 0.1335 -0.0454
MDA-MB-231 WZ-4-145
0.04
uM
LJP6
 72
hr
 1235 3498 4513 0.7751 0.6903
MCF 10A WZ-4-145
0.12
uM
LJP6
 72
hr
 962 9948 10605 0.9381 0.9319
Hs 578T WZ-4-145
0.37
uM
LJP6
 72
hr
 658 2117 3846 0.5504 0.4576
MCF 10A WZ-4-145
0.04
uM
LJP6
 72
hr
 962 10423 10605 0.9829 0.9812
Hs 578T WZ-4-145
3.33
uM
LJP6
 72
hr
 658 1626 3846 0.4229 0.3038
BT-20 WZ-4-145
1.11
uM
LJP6
 72
hr
 1097 2177 3769 0.5777 0.4043