LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
BT-20 Crizotinib
3.33
uM
LJP5
 72
hr
 1097 1566 3769 0.4156 0.1757
BT-20 Dasatinib
3.33
uM
LJP6
 72
hr
 1097 985 3769 0.2615 -0.0418
BT-20 Dovitinib
3.33
uM
LJP5
 72
hr
 1097 1500 3769 0.3981 0.1510
BT-20 Erlotinib
3.33
uM
LJP5
 72
hr
 1097 3231 3769 0.8573 0.7987
BT-20 Foretinib
3.33
uM
LJP5
 72
hr
 1097 1303 3769 0.3458 0.0772
BT-20 Afatinib
3.33
uM
LJP6
 72
hr
 1097 3253 3769 0.8631 0.8068
BT-20 Sigma A6730
3.33
uM
LJP5
 72
hr
 1097 3334 3769 0.8845 0.8370
BT-20 AT-7519
3.33
uM
LJP6
 72
hr
 1097 540 3769 0.1433 -0.2085
BT-20 AZD 5438
3.33
uM
LJP6
 72
hr
 1097 761 3769 0.2021 -0.1256
BT-20 AZD8055
3.33
uM
LJP6
 72
hr
 1097 906 3769 0.2405 -0.0713
BT-20 AZD8330
3.33
uM
LJP5
 72
hr
 1097 3168 3769 0.8404 0.7749
BT-20 BI-2536
3.33
uM
LJP6
 72
hr
 1097 875 3769 0.2321 -0.0832
BT-20 BMS345541
3.33
uM
LJP6
 72
hr
 1097 2738 3769 0.7264 0.6141
BT-20 SB590885
3.33
uM
LJP5
 72
hr
 1097 4026 3769 1.0681 1.0961
BT-20 PIK-93
3.33
uM
LJP5
 72
hr
 1097 3007 3769 0.7977 0.7147
BT-20 Alpelisib
3.33
uM
LJP5
 72
hr
 1097 1241 3769 0.3292 0.0538
BT-20 Luminespib
3.33
uM
LJP5
 72
hr
 1097 1139 3769 0.3023 0.0159
BT-20 XMD11-85h
3.33
uM
LJP6
 72
hr
 1097 2962 3769 0.7859 0.6979
BT-20 HG-6-64-01
3.33
uM
LJP6
 72
hr
 1097 1560 3769 0.4140 0.1734
BT-20 WZ-4-145
3.33
uM
LJP6
 72
hr
 1097 2046 3769 0.5428 0.3550
BT-20 XMD16-144
3.33
uM
LJP5
 72
hr
 1097 1312 3769 0.3481 0.0804
BT-20 Celastrol
3.33
uM
LJP6
 72
hr
 1097 477 3769 0.1266 -0.2320
BT-20 CGP60474
3.33
uM
LJP5
 72
hr
 1097 593 3769 0.1574 -0.1886
BT-20 Geldanamycin
3.33
uM
LJP6
 72
hr
 1097 891 3769 0.2365 -0.0771
BT-20 Geldanamycin
3.33
uM
LJP5
 72
hr
 1097 936 3769 0.2483 -0.0603