LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A Crizotinib
0.04
uM
LJP5
 72
hr
 962 10700 10605 1.0090 1.0099
MCF 10A Dasatinib
0.04
uM
LJP6
 72
hr
 962 2885 10605 0.2721 0.1995
MCF 10A Dovitinib
0.04
uM
LJP5
 72
hr
 962 10483 10605 0.9886 0.9874
MCF 10A Erlotinib
0.04
uM
LJP5
 72
hr
 962 9767 10605 0.9210 0.9131
MCF 10A Foretinib
0.04
uM
LJP5
 72
hr
 962 10370 10605 0.9779 0.9757
MCF 10A Afatinib
0.04
uM
LJP6
 72
hr
 962 1713 10605 0.1616 0.0779
MCF 10A Sigma A6730
0.04
uM
LJP5
 72
hr
 962 10574 10605 0.9971 0.9968
MCF 10A AT-7519
0.04
uM
LJP6
 72
hr
 962 9592 10605 0.9045 0.8950
MCF 10A AZD 5438
0.04
uM
LJP6
 72
hr
 962 9619 10605 0.9071 0.8978
MCF 10A AZD8055
0.04
uM
LJP6
 72
hr
 962 3374 10605 0.3182 0.2502
MCF 10A AZD8330
0.04
uM
LJP5
 72
hr
 962 1546 10605 0.1458 0.0606
MCF 10A BI-2536
0.04
uM
LJP6
 72
hr
 962 786 10605 0.0741 -0.0183
MCF 10A BMS345541
0.04
uM
LJP6
 72
hr
 962 10478 10605 0.9881 0.9869
MCF 10A SB590885
0.04
uM
LJP5
 72
hr
 962 8969 10605 0.8458 0.8304
MCF 10A PIK-93
0.04
uM
LJP5
 72
hr
 962 10362 10605 0.9771 0.9748
MCF 10A Alpelisib
0.04
uM
LJP5
 72
hr
 962 10528 10605 0.9928 0.9921
MCF 10A Luminespib
0.04
uM
LJP5
 72
hr
 962 834 10605 0.0786 -0.0133
MCF 10A XMD11-85h
0.04
uM
LJP6
 72
hr
 962 10945 10605 1.0321 1.0353
MCF 10A HG-6-64-01
0.04
uM
LJP6
 72
hr
 962 10078 10605 0.9503 0.9453
MCF 10A WZ-4-145
0.04
uM
LJP6
 72
hr
 962 10423 10605 0.9829 0.9812
MCF 10A XMD16-144
0.04
uM
LJP5
 72
hr
 962 2697 10605 0.2543 0.1799
MCF 10A Celastrol
0.04
uM
LJP6
 72
hr
 962 11411 10605 1.0760 1.0836
MCF 10A CGP60474
0.04
uM
LJP5
 72
hr
 962 4799 10605 0.4526 0.3979
MCF 10A Geldanamycin
0.04
uM
LJP6
 72
hr
 962 1229 10605 0.1159 0.0277
MCF 10A Geldanamycin
0.04
uM
LJP5
 72
hr
 962 1729 10605 0.1630 0.0795