LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Timepoint | Timepoint Unit | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | Crizotinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3728 | 4223 | 0.8828 | 0.8245 |
| SK-BR-3 | Dasatinib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3799 | 4223 | 0.8997 | 0.8499 |
| SK-BR-3 | Dovitinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3691 | 4223 | 0.8742 | 0.8117 |
| SK-BR-3 | Erlotinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3713 | 4223 | 0.8792 | 0.8192 |
| SK-BR-3 | Foretinib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4620 | 4223 | 1.0941 | 1.1409 |
| SK-BR-3 | Afatinib | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1437 | 4223 | 0.3404 | 0.0127 |
| SK-BR-3 | Sigma A6730 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3699 | 4223 | 0.8760 | 0.8144 |
| SK-BR-3 | AT-7519 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2511 | 4223 | 0.5948 | 0.3935 |
| SK-BR-3 | AZD 5438 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3734 | 4223 | 0.8843 | 0.8268 |
| SK-BR-3 | AZD8055 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1460 | 4223 | 0.3457 | 0.0207 |
| SK-BR-3 | AZD8330 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 3062 | 4223 | 0.7251 | 0.5886 |
| SK-BR-3 | BI-2536 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1352 | 4223 | 0.3203 | -0.0173 |
| SK-BR-3 | BMS345541 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4336 | 4223 | 1.0268 | 1.0401 |
| SK-BR-3 | SB590885 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4804 | 4223 | 1.1377 | 1.2061 |
| SK-BR-3 | PIK-93 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4442 | 4223 | 1.0519 | 1.0777 |
| SK-BR-3 | Alpelisib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4129 | 4223 | 0.9778 | 0.9668 |
| SK-BR-3 | Luminespib | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1644 | 4223 | 0.3893 | 0.0859 |
| SK-BR-3 | XMD11-85h | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3250 | 4223 | 0.7697 | 0.6554 |
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 4507 | 4223 | 1.0674 | 1.1009 |
| SK-BR-3 | WZ-4-145 | 0.04 | uM | LJP6 | 72 | hr | 1401 | 2442 | 4223 | 0.5783 | 0.3689 |
| SK-BR-3 | XMD16-144 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1628 | 4223 | 0.3856 | 0.0804 |
| SK-BR-3 | Celastrol | 0.04 | uM | LJP6 | 72 | hr | 1401 | 3226 | 4223 | 0.7640 | 0.6467 |
| SK-BR-3 | CGP60474 | 0.04 | uM | LJP5 | 72 | hr | 1401 | 4452 | 4223 | 1.0542 | 1.0811 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP6 | 72 | hr | 1401 | 1637 | 4223 | 0.3877 | 0.0836 |
| SK-BR-3 | Geldanamycin | 0.04 | uM | LJP5 | 72 | hr | 1401 | 1826 | 4223 | 0.4324 | 0.1504 |