LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A LDN-193189
10.0
uM
LJP5
 72
hr
 962 136 10605 0.0128 -0.0857
MDA-MB-231 PHA-665752
10.0
uM
LJP5
 72
hr
 1235 131 4513 0.0291 -0.3370
Hs 578T SB590885
10.0
uM
LJP5
 72
hr
 658 125 3846 0.0327 -0.1670
BT-20 AZD8055
10.0
uM
LJP6
 72
hr
 1097 119 3769 0.0317 -0.3658
SK-BR-3 Mitoxantrone
10.0
uM
LJP6
 72
hr
 1401 109 4223 0.0258 -0.4581
MDA-MB-231 Mitoxantrone
10.0
uM
LJP6
 72
hr
 1235 108 4513 0.0241 -0.3439
Hs 578T AZD8055
10.0
uM
LJP6
 72
hr
 658 103 3846 0.0270 -0.1739
SK-BR-3 Mitoxantrone
10.0
uM
LJP5
 72
hr
 1401 91 4223 0.0217 -0.4642
MCF7 Mitoxantrone
10.0
uM
LJP5
 72
hr
 1209 89 4093 0.0219 -0.3884
MDA-MB-231 Mitoxantrone
10.0
uM
LJP5
 72
hr
 1235 86 4513 0.0191 -0.3507
MCF7 Mitoxantrone
10.0
uM
LJP6
 72
hr
 1209 70 4093 0.0171 -0.3952
MCF 10A AZD8055
10.0
uM
LJP6
 72
hr
 962 57 10605 0.0054 -0.0939
Hs 578T PHA-665752
10.0
uM
LJP5
 72
hr
 658 53 3846 0.0140 -0.1896
Hs 578T Mitoxantrone
10.0
uM
LJP6
 72
hr
 658 35 3846 0.0091 -0.1955
Hs 578T Mitoxantrone
10.0
uM
LJP5
 72
hr
 658 25 3846 0.0065 -0.1986