LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 6 of 15: Mean cell count and mean growth rate across biological replicate 3. - Dataset (ID:20242)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
SK-BR-3 Trametinib
3.33
uM
LJP5
 72
hr
 1401 3487 4223 0.8258 0.7392
MCF 10A PHA-665752
10.0
uM
LJP5
 72
hr
 962 5979 10605 0.5639 0.5203
SK-BR-3 Radicicol
1.11
uM
LJP5
 72
hr
 1401 1652 4223 0.3913 0.0889
MDA-MB-231 WZ3105
0.37
uM
LJP5
 72
hr
 1235 461 4513 0.1022 -0.2363
MCF 10A PLX-4720
10.0
uM
LJP5
 72
hr
 962 8942 10605 0.8432 0.8276
SK-BR-3 TWS119
3.33
uM
LJP5
 72
hr
 1401 3029 4223 0.7173 0.5768
SK-BR-3 Seliciclib
1.11
uM
LJP5
 72
hr
 1401 3763 4223 0.8911 0.8369
MCF 10A Radicicol
10.0
uM
LJP5
 72
hr
 962 495 10605 0.0467 -0.0484
MDA-MB-231 YM 201636
0.37
uM
LJP5
 72
hr
 1235 3734 4513 0.8273 0.7622
MCF 10A Seliciclib
10.0
uM
LJP5
 72
hr
 962 4858 10605 0.4581 0.4040
MCF 10A Ruxolitinib
10.0
uM
LJP5
 72
hr
 962 7375 10605 0.6954 0.6650
MCF 10A XL147
10.0
uM
LJP5
 72
hr
 962 4368 10605 0.4119 0.3532
SK-BR-3 Ruxolitinib
1.11
uM
LJP5
 72
hr
 1401 4115 4223 0.9746 0.9619
SK-BR-3 LDN-193189
0.12
uM
LJP5
 72
hr
 1401 4081 4223 0.9664 0.9498
MDA-MB-231 Sigma A6730
1.11
uM
LJP5
 72
hr
 1235 4267 4513 0.9454 0.9249