LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 4 of 15: Mean cell count and mean growth rate across biological replicate 1. - Dataset (ID:20240)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Timepoint Timepoint Unit Mean Total Cell Count Before Treatment Mean Total Cell Count After Treatment Mean Total Control Cell Count Mean Relative Cell Count Mean Relative Growth Rate After Treatment
MCF 10A A443654
0.12
uM
LJP6
 72
hr
 513 2023 10401 0.1946 0.1527
MCF7 A443654
3.33
uM
LJP6
 72
hr
 1235 584 4156 0.1405 -0.2230
MCF 10A A443654
0.04
uM
LJP6
 72
hr
 513 4000 10401 0.3846 0.3527
BT-20 A443654
0.37
uM
LJP6
 72
hr
 1657 1495 5505 0.2716 -0.0422
MCF 10A A443654
0.37
uM
LJP6
 72
hr
 513 692 10401 0.0666 0.0181
Hs 578T A443654
0.37
uM
LJP6
 72
hr
 929 952 3228 0.2950 0.0100
BT-20 A443654
3.33
uM
LJP6
 72
hr
 1657 1142 5505 0.2075 -0.1339
BT-20 A443654
10.0
uM
LJP6
 72
hr
 1657 652 5505 0.1185 -0.2613
Hs 578T A443654
0.04
uM
LJP6
 72
hr
 929 2096 3228 0.6494 0.5077
Hs 578T A443654
0.12
uM
LJP6
 72
hr
 929 1547 3228 0.4794 0.2690
MCF 10A A443654
3.33
uM
LJP6
 72
hr
 513 351 10401 0.0338 -0.0164
MCF 10A Afatinib
0.37
uM
LJP6
 72
hr
 513 487 10401 0.0469 -0.0026
MCF 10A Afatinib
1.11
uM
LJP6
 72
hr
 513 588 10401 0.0566 0.0076
Hs 578T Afatinib
1.11
uM
LJP6
 72
hr
 929 2985 3228 0.9249 0.8946
Hs 578T Afatinib
10.0
uM
LJP6
 72
hr
 929 736 3228 0.2281 -0.0839
MCF7 Afatinib
10.0
uM
LJP6
 72
hr
 1235 664 4156 0.1598 -0.1955
MDA-MB-231 Afatinib
0.04
uM
LJP6
 72
hr
 868 2549 3486 0.7313 0.6422
MCF7 Afatinib
1.11
uM
LJP6
 72
hr
 1235 3186 4156 0.7667 0.6681
Hs 578T Afatinib
0.04
uM
LJP6
 72
hr
 929 3069 3228 0.9509 0.9311
MCF7 Afatinib
3.33
uM
LJP6
 72
hr
 1235 2283 4156 0.5495 0.3589
Hs 578T Afatinib
0.12
uM
LJP6
 72
hr
 929 3002 3228 0.9301 0.9018
Hs 578T Afatinib
3.33
uM
LJP6
 72
hr
 929 2740 3228 0.8488 0.7877
BT-20 Afatinib
3.33
uM
LJP6
 72
hr
 1657 4854 5505 0.8817 0.8307
MCF7 Afatinib
0.04
uM
LJP6
 72
hr
 1235 2830 4156 0.6811 0.5462
MCF7 Afatinib
0.12
uM
LJP6
 72
hr
 1235 2890 4156 0.6955 0.5667