LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
MCF 10A Withaferin A
0.12
uM
LJP5
2
G17
72
hr
962 10973 10605 1.0347 1.0382
MCF 10A Lapatinib
0.12
uM
LJP6
3
M23
72
hr
962 10513 10605 0.9913 0.9905
MCF 10A Crizotinib
10.0
uM
LJP5
1
A19
72
hr
962 1318 10605 0.1243 0.0369
MCF 10A Sorafenib
0.04
uM
LJP6
3
B12
72
hr
962 10633 10605 1.0026 1.0029
MCF 10A HG-5-113-01
0.12
uM
LJP5
2
B11
72
hr
962 9527 10605 0.8983 0.8882
MCF 10A OSI-027
3.33
uM
LJP6
1
E08
72
hr
962 1721 10605 0.1623 0.0787
MCF 10A Fedratinib
3.33
uM
LJP5
1
L02
72
hr
962 3813 10605 0.3595 0.2956
MCF 10A Erlotinib
0.12
uM
LJP5
3
M23
72
hr
962 5629 10605 0.5308 0.4840
MCF 10A PD0325901
1.11
uM
LJP5
1
C03
72
hr
962 1993 10605 0.1879 0.1069
MCF 10A AZD7762
1.11
uM
LJP6
1
L03
72
hr
962 3406 10605 0.3212 0.2534
MCF 10A JNK-9L
0.37
uM
LJP6
3
K22
72
hr
962 5683 10605 0.5359 0.4896
MCF 10A Withaferin A
0.12
uM
LJP6
1
G17
72
hr
962 9773 10605 0.9215 0.9137
MCF 10A TGX221
0.04
uM
LJP5
1
H24
72
hr
962 9863 10605 0.9300 0.9230
MCF 10A HG-5-113-01
0.12
uM
LJP5
1
B11
72
hr
962 10186 10605 0.9605 0.9565
MCF 10A SU11274
3.33
uM
LJP5
3
J08
72
hr
962 6697 10605 0.6315 0.5947
MCF 10A PD0325901
1.11
uM
LJP5
3
C03
72
hr
962 1770 10605 0.1669 0.0838
MCF 10A JW-7-24-1
0.37
uM
LJP6
2
B22
72
hr
962 9647 10605 0.9097 0.9006
MCF 10A CP466722
10.0
uM
LJP5
1
I07
72
hr
962 5639 10605 0.5317 0.4850
MCF 10A Fedratinib
3.33
uM
LJP5
2
L02
72
hr
962 4322 10605 0.4075 0.3484
MCF 10A Enzastaurin
3.33
uM
LJP5
1
D14
72
hr
962 11827 10605 1.1152 1.1267