LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | CP466722 | 0.37 | uM | LJP5 | 2 | I10 | 72 | hr | 1235 | 1 | 4513 | 0.0002 | -0.3768 |
| MDA-MB-231 | Torin2 | 3.33 | uM | LJP5 | 1 | I20 | 72 | hr | 1235 | 1 | 4513 | 0.0002 | -0.3768 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP5 | 2 | C19 | 72 | hr | 658 | 19 | 3846 | 0.0049 | -0.2005 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP6 | 2 | C19 | 72 | hr | 658 | 23 | 3846 | 0.0060 | -0.1993 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP5 | 1 | C19 | 72 | hr | 658 | 24 | 3846 | 0.0062 | -0.1989 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP5 | 3 | C19 | 72 | hr | 658 | 32 | 3846 | 0.0083 | -0.1964 |
| Hs 578T | PHA-665752 | 10.0 | uM | LJP5 | 1 | F13 | 72 | hr | 658 | 37 | 3846 | 0.0096 | -0.1949 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP6 | 3 | C19 | 72 | hr | 658 | 41 | 3846 | 0.0107 | -0.1936 |
| Hs 578T | Mitoxantrone | 10.0 | uM | LJP6 | 1 | C19 | 72 | hr | 658 | 41 | 3846 | 0.0107 | -0.1936 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 962 | 50 | 10605 | 0.0047 | -0.0946 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 962 | 57 | 10605 | 0.0054 | -0.0939 |
| Hs 578T | PHA-665752 | 10.0 | uM | LJP5 | 3 | F13 | 72 | hr | 658 | 62 | 3846 | 0.0161 | -0.1870 |
| Hs 578T | PHA-665752 | 10.0 | uM | LJP5 | 2 | F13 | 72 | hr | 658 | 62 | 3846 | 0.0161 | -0.1870 |
| MCF 10A | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 962 | 64 | 10605 | 0.0060 | -0.0931 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP6 | 2 | C19 | 72 | hr | 1209 | 68 | 4093 | 0.0166 | -0.3959 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP6 | 1 | C19 | 72 | hr | 1209 | 69 | 4093 | 0.0169 | -0.3956 |
| SK-BR-3 | Mitoxantrone | 10.0 | uM | LJP5 | 3 | C19 | 72 | hr | 1401 | 73 | 4223 | 0.0173 | -0.4709 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP6 | 3 | C19 | 72 | hr | 1209 | 73 | 4093 | 0.0178 | -0.3942 |
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP5 | 2 | C19 | 72 | hr | 1235 | 75 | 4513 | 0.0166 | -0.3542 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP5 | 2 | C19 | 72 | hr | 1209 | 78 | 4093 | 0.0191 | -0.3924 |
| SK-BR-3 | Mitoxantrone | 10.0 | uM | LJP5 | 1 | C19 | 72 | hr | 1401 | 80 | 4223 | 0.0189 | -0.4684 |
| Hs 578T | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 658 | 80 | 3846 | 0.0208 | -0.1814 |
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP5 | 3 | C19 | 72 | hr | 1235 | 88 | 4513 | 0.0195 | -0.3502 |
| MCF 10A | LDN-193189 | 10.0 | uM | LJP5 | 2 | G01 | 72 | hr | 962 | 89 | 10605 | 0.0084 | -0.0905 |
| MCF7 | Mitoxantrone | 10.0 | uM | LJP5 | 1 | C19 | 72 | hr | 1209 | 90 | 4093 | 0.0220 | -0.3883 |