LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP5 | 3 | C19 | 72 | hr | 1235 | 88 | 4513 | 0.0195 | -0.3502 |
| SK-BR-3 | LDN-193189 | 3.33 | uM | LJP5 | 1 | G02 | 72 | hr | 1401 | 418 | 4223 | 0.0990 | -0.3486 |
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP5 | 1 | C19 | 72 | hr | 1235 | 96 | 4513 | 0.0213 | -0.3478 |
| MCF7 | JNK-9L | 10.0 | uM | LJP6 | 1 | K19 | 72 | hr | 1209 | 207 | 4093 | 0.0506 | -0.3477 |
| BT-20 | Mitoxantrone | 10.0 | uM | LJP5 | 1 | C19 | 72 | hr | 1097 | 168 | 3769 | 0.0446 | -0.3477 |
| MDA-MB-231 | HG-6-64-01 | 10.0 | uM | LJP6 | 2 | M01 | 72 | hr | 1235 | 98 | 4513 | 0.0217 | -0.3472 |
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP6 | 1 | C19 | 72 | hr | 1235 | 102 | 4513 | 0.0226 | -0.3460 |
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP6 | 3 | C19 | 72 | hr | 1235 | 104 | 4513 | 0.0230 | -0.3454 |
| SK-BR-3 | AZD8055 | 10.0 | uM | LJP6 | 1 | A07 | 72 | hr | 1401 | 429 | 4223 | 0.1016 | -0.3447 |
| BT-20 | Mitoxantrone | 10.0 | uM | LJP5 | 3 | C19 | 72 | hr | 1097 | 182 | 3769 | 0.0483 | -0.3425 |
| SK-BR-3 | AZD8055 | 10.0 | uM | LJP6 | 2 | A07 | 72 | hr | 1401 | 438 | 4223 | 0.1037 | -0.3415 |
| MCF7 | JNK-9L | 10.0 | uM | LJP6 | 3 | K19 | 72 | hr | 1209 | 227 | 4093 | 0.0555 | -0.3408 |
| MCF7 | HG-6-64-01 | 10.0 | uM | LJP6 | 3 | M01 | 72 | hr | 1209 | 227 | 4093 | 0.0555 | -0.3408 |
| BT-20 | Mitoxantrone | 10.0 | uM | LJP6 | 3 | C19 | 72 | hr | 1097 | 187 | 3769 | 0.0496 | -0.3406 |
| MDA-MB-231 | Mitoxantrone | 10.0 | uM | LJP6 | 2 | C19 | 72 | hr | 1235 | 120 | 4513 | 0.0266 | -0.3405 |
| MDA-MB-231 | AT-7519 | 10.0 | uM | LJP6 | 2 | K01 | 72 | hr | 1235 | 122 | 4513 | 0.0270 | -0.3399 |
| BT-20 | Mitoxantrone | 10.0 | uM | LJP6 | 2 | C19 | 72 | hr | 1097 | 194 | 3769 | 0.0515 | -0.3380 |
| MDA-MB-231 | PHA-665752 | 10.0 | uM | LJP5 | 2 | F13 | 72 | hr | 1235 | 130 | 4513 | 0.0288 | -0.3374 |
| MDA-MB-231 | PHA-665752 | 10.0 | uM | LJP5 | 3 | F13 | 72 | hr | 1235 | 131 | 4513 | 0.0290 | -0.3371 |
| MDA-MB-231 | PHA-665752 | 10.0 | uM | LJP5 | 1 | F13 | 72 | hr | 1235 | 133 | 4513 | 0.0295 | -0.3365 |
| MDA-MB-231 | AT-7519 | 3.33 | uM | LJP6 | 2 | K02 | 72 | hr | 1235 | 136 | 4513 | 0.0301 | -0.3356 |
| SK-BR-3 | GSK1059615 | 3.33 | uM | LJP5 | 1 | E02 | 72 | hr | 1401 | 458 | 4223 | 0.1085 | -0.3344 |
| SK-BR-3 | AZD8055 | 10.0 | uM | LJP6 | 3 | A07 | 72 | hr | 1401 | 463 | 4223 | 0.1096 | -0.3326 |
| MDA-MB-231 | Geldanamycin | 10.0 | uM | LJP6 | 2 | O01 | 72 | hr | 1235 | 149 | 4513 | 0.0330 | -0.3316 |
| MDA-MB-231 | CGP60474 | 3.33 | uM | LJP6 | 2 | G02 | 72 | hr | 1235 | 160 | 4513 | 0.0354 | -0.3283 |