LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 3 of 15: Cell count and relative growth within biological replicate 3. - Dataset (ID:20239)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 Omipalisib
1.11
uM
LJP6
 2
N03
 72
hr
 1401 1054 4223 0.2496 -0.1232
SK-BR-3 Fedratinib
1.11
uM
LJP5
 1
L03
 72
hr
 1401 3319 4223 0.7859 0.6796
SK-BR-3 BX-912
3.33
uM
LJP5
 1
L20
 72
hr
 1401 1406 4223 0.3329 0.0016
SK-BR-3 Canertinib
0.04
uM
LJP6
 2
H12
 72
hr
 1401 1782 4223 0.4220 0.1349
SK-BR-3 Pelitinib
0.04
uM
LJP5
 3
I18
 72
hr
 1401 2419 4223 0.5728 0.3606
SK-BR-3 PHA-665752
10.0
uM
LJP5
 2
F13
 72
hr
 1401 1095 4223 0.2593 -0.1086
SK-BR-3 WYE-125132
0.04
uM
LJP6
 3
L12
 72
hr
 1401 1790 4223 0.4239 0.1377
SK-BR-3 PF477736
0.04
uM
LJP5
 3
J24
 72
hr
 1401 1932 4223 0.4575 0.1880
SK-BR-3 NVP-AEW541
0.04
uM
LJP5
 3
E18
 72
hr
 1401 4018 4223 0.9514 0.9273
SK-BR-3 BI-2536
0.37
uM
LJP6
 1
D16
 72
hr
 1401 1512 4223 0.3580 0.0392
SK-BR-3 Radicicol
0.37
uM
LJP5
 3
K10
 72
hr
 1401 1514 4223 0.3585 0.0399
SK-BR-3 GSK1904529A
1.11
uM
LJP6
 2
H21
 72
hr
 1401 4047 4223 0.9583 0.9376
SK-BR-3 BX-912
3.33
uM
LJP5
 2
L20
 72
hr
 1401 1448 4223 0.3429 0.0165
SK-BR-3 Pelitinib
0.04
uM
LJP5
 1
I18
 72
hr
 1401 2084 4223 0.4935 0.2419
SK-BR-3 WZ3105
0.04
uM
LJP5
 1
D24
 72
hr
 1401 894 4223 0.2117 -0.1799
SK-BR-3 Y39983
0.12
uM
LJP6
 3
P05
 72
hr
 1401 4264 4223 1.0097 1.0145
SK-BR-3 PLX-4720
0.37
uM
LJP5
 1
K04
 72
hr
 1401 3099 4223 0.7338 0.6016
SK-BR-3 BX-912
3.33
uM
LJP5
 3
L20
 72
hr
 1401 1415 4223 0.3351 0.0048
SK-BR-3 Saracatinib
0.04
uM
LJP6
 1
D12
 72
hr
 1401 4287 4223 1.0151 1.0227
SK-BR-3 PLX-4720
0.37
uM
LJP5
 2
K04
 72
hr
 1401 4287 4223 1.0151 1.0227