LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Sorafenib | 0.12 | uM | LJP6 | 1 | B11 | 72 | hr | 1694 | 12219 | 11155 | 1.0953 | 1.1124 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 1 | L15 | 72 | hr | 1694 | 12264 | 11155 | 1.0994 | 1.1171 |
| MCF 10A | Sirolimus | 10.0 | uM | LJP6 | 1 | L13 | 72 | hr | 1694 | 12294 | 11155 | 1.1020 | 1.1203 |
| MCF 10A | Sirolimus | 0.04 | uM | LJP6 | 1 | L18 | 72 | hr | 1694 | 12335 | 11155 | 1.1057 | 1.1246 |
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 3 | G11 | 72 | hr | 1694 | 12367 | 11155 | 1.1086 | 1.1280 |
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 2 | G11 | 72 | hr | 1694 | 12369 | 11155 | 1.1088 | 1.1282 |
| MCF 10A | Sirolimus | 0.04 | uM | LJP6 | 2 | L18 | 72 | hr | 1694 | 12381 | 11155 | 1.1098 | 1.1295 |
| MCF 10A | Sorafenib | 0.04 | uM | LJP6 | 1 | B12 | 72 | hr | 1694 | 12387 | 11155 | 1.1104 | 1.1301 |
| MCF 10A | Sirolimus | 10.0 | uM | LJP6 | 3 | L13 | 72 | hr | 1694 | 12399 | 11155 | 1.1115 | 1.1314 |
| MCF 10A | Sirolimus | 0.12 | uM | LJP6 | 1 | L17 | 72 | hr | 1694 | 12403 | 11155 | 1.1118 | 1.1318 |
| MCF 10A | Sirolimus | 0.37 | uM | LJP6 | 1 | L16 | 72 | hr | 1694 | 12413 | 11155 | 1.1127 | 1.1329 |
| MCF 10A | Celastrol | 0.12 | uM | LJP6 | 1 | G11 | 72 | hr | 1694 | 12496 | 11155 | 1.1201 | 1.1417 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 3 | L15 | 72 | hr | 1694 | 12507 | 11155 | 1.1211 | 1.1428 |
| MCF 10A | Sirolimus | 0.37 | uM | LJP6 | 3 | L16 | 72 | hr | 1694 | 12517 | 11155 | 1.1220 | 1.1439 |
| MCF 10A | Sirolimus | 3.33 | uM | LJP6 | 1 | L14 | 72 | hr | 1694 | 12547 | 11155 | 1.1247 | 1.1471 |
| MCF 10A | Sirolimus | 0.12 | uM | LJP6 | 2 | L17 | 72 | hr | 1694 | 12573 | 11155 | 1.1271 | 1.1498 |
| MCF 10A | Sirolimus | 10.0 | uM | LJP6 | 2 | L13 | 72 | hr | 1694 | 12630 | 11155 | 1.1322 | 1.1558 |
| MCF 10A | Sirolimus | 1.11 | uM | LJP6 | 2 | L15 | 72 | hr | 1694 | 12668 | 11155 | 1.1356 | 1.1598 |
| MCF 10A | Sirolimus | 0.37 | uM | LJP6 | 2 | L16 | 72 | hr | 1694 | 12672 | 11155 | 1.1359 | 1.1603 |
| MCF 10A | Sirolimus | 3.33 | uM | LJP6 | 3 | L14 | 72 | hr | 1694 | 12682 | 11155 | 1.1368 | 1.1613 |
| MCF 10A | QL-X-138 | 0.04 | uM | LJP6 | 2 | F24 | 72 | hr | 1694 | 12701 | 11155 | 1.1385 | 1.1633 |
| MCF 10A | Sirolimus | 3.33 | uM | LJP6 | 2 | L14 | 72 | hr | 1694 | 12883 | 11155 | 1.1548 | 1.1826 |