LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Hs 578T | WZ3105 | 10.0 | uM | LJP5 | 2 | D19 | 72 | hr | 765 | 394 | 3124 | 0.1261 | -0.1573 |
| BT-20 | SNS-032 | 3.33 | uM | LJP6 | 2 | H14 | 72 | hr | 1334 | 394 | 3970 | 0.0992 | -0.3568 |
| BT-20 | SNS-032 | 1.11 | uM | LJP6 | 1 | H15 | 72 | hr | 1334 | 395 | 3970 | 0.0995 | -0.3565 |
| Hs 578T | Buparlisib | 3.33 | uM | LJP5 | 3 | H02 | 72 | hr | 765 | 395 | 3124 | 0.1264 | -0.1568 |
| Hs 578T | CGP60474 | 1.11 | uM | LJP5 | 2 | F03 | 72 | hr | 765 | 396 | 3124 | 0.1267 | -0.1564 |
| BT-20 | CGP60474 | 1.11 | uM | LJP6 | 3 | G03 | 72 | hr | 1334 | 396 | 3970 | 0.0997 | -0.3561 |
| Hs 578T | JW-7-24-1 | 10.0 | uM | LJP6 | 2 | B19 | 72 | hr | 765 | 396 | 3124 | 0.1267 | -0.1564 |
| Hs 578T | Geldanamycin | 10.0 | uM | LJP5 | 1 | O01 | 72 | hr | 765 | 396 | 3124 | 0.1267 | -0.1564 |
| Hs 578T | SNS-032 | 0.12 | uM | LJP6 | 1 | H17 | 72 | hr | 765 | 397 | 3124 | 0.1271 | -0.1560 |
| Hs 578T | SNS-032 | 10.0 | uM | LJP6 | 3 | H13 | 72 | hr | 765 | 397 | 3124 | 0.1271 | -0.1560 |
| Hs 578T | CGP60474 | 1.11 | uM | LJP6 | 3 | G03 | 72 | hr | 765 | 398 | 3124 | 0.1274 | -0.1556 |
| Hs 578T | WZ3105 | 3.33 | uM | LJP5 | 1 | D20 | 72 | hr | 765 | 398 | 3124 | 0.1274 | -0.1556 |
| Hs 578T | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 765 | 398 | 3124 | 0.1274 | -0.1556 |
| Hs 578T | Dasatinib | 3.33 | uM | LJP6 | 1 | I02 | 72 | hr | 765 | 398 | 3124 | 0.1274 | -0.1556 |
| MCF7 | CGP60474 | 3.33 | uM | LJP5 | 3 | F02 | 72 | hr | 1389 | 398 | 5667 | 0.0702 | -0.2316 |
| Hs 578T | Alvocidib | 0.37 | uM | LJP6 | 3 | A16 | 72 | hr | 765 | 399 | 3124 | 0.1277 | -0.1551 |
| Hs 578T | CGP60474 | 1.11 | uM | LJP6 | 1 | G03 | 72 | hr | 765 | 399 | 3124 | 0.1277 | -0.1551 |
| Hs 578T | PHA-665752 | 10.0 | uM | LJP5 | 2 | F13 | 72 | hr | 765 | 399 | 3124 | 0.1277 | -0.1551 |
| MCF 10A | CGP60474 | 0.37 | uM | LJP6 | 3 | G04 | 72 | hr | 1694 | 400 | 11155 | 0.0359 | -0.1368 |
| Hs 578T | CGP60474 | 3.33 | uM | LJP5 | 2 | F02 | 72 | hr | 765 | 401 | 3124 | 0.1283 | -0.1543 |
| BT-20 | SNS-032 | 1.11 | uM | LJP6 | 2 | H15 | 72 | hr | 1334 | 401 | 3970 | 0.1010 | -0.3542 |
| Hs 578T | PHA-793887 | 10.0 | uM | LJP6 | 3 | E19 | 72 | hr | 765 | 401 | 3124 | 0.1283 | -0.1543 |
| MCF 10A | CGP60474 | 0.04 | uM | LJP6 | 3 | G06 | 72 | hr | 1694 | 401 | 11155 | 0.0359 | -0.1367 |
| BT-20 | SNS-032 | 3.33 | uM | LJP6 | 3 | H14 | 72 | hr | 1334 | 401 | 3970 | 0.1010 | -0.3542 |
| Hs 578T | AT-7519 | 10.0 | uM | LJP6 | 3 | K01 | 72 | hr | 765 | 401 | 3124 | 0.1283 | -0.1543 |