LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
BT-20 Alpelisib
0.37
uM
LJP5
 2
N04
 72
hr
 1334 3259 3970 0.8207 0.7300
BT-20 Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 1334 3325 3970 0.8373 0.7550
Hs 578T Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 765 2524 3124 0.8078 0.7455
MCF7 Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 1389 2856 5667 0.5039 0.3428
Hs 578T Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 765 2879 3124 0.9214 0.8959
Hs 578T Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 765 2859 3124 0.9150 0.8875
MCF 10A Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 1694 8328 11155 0.7465 0.7011
MCF7 Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 1389 3713 5667 0.6551 0.5431
Hs 578T Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 765 2916 3124 0.9333 0.9116
Hs 578T Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 765 2472 3124 0.7912 0.7234
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 2
N03
 72
hr
 1311 4607 5013 0.9189 0.8902
MCF 10A Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 1694 8270 11155 0.7413 0.6950
MCF7 Alpelisib
0.37
uM
LJP5
 3
N04
 72
hr
 1389 4022 5667 0.7096 0.6153
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 3
N03
 72
hr
 1311 4980 5013 0.9933 0.9909
MCF 10A Alpelisib
0.12
uM
LJP5
 1
N05
 72
hr
 1694 9939 11155 0.8909 0.8714
MCF 10A Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 1694 9738 11155 0.8729 0.8502
MCF 10A Alpelisib
0.12
uM
LJP5
 2
N05
 72
hr
 1694 9702 11155 0.8697 0.8464
Hs 578T Alpelisib
3.33
uM
LJP5
 1
N02
 72
hr
 765 2286 3124 0.7316 0.6446
Hs 578T Alpelisib
10.0
uM
LJP5
 3
N01
 72
hr
 765 1719 3124 0.5502 0.4043
MCF 10A Alpelisib
0.12
uM
LJP5
 3
N05
 72
hr
 1694 10344 11155 0.9272 0.9142
Hs 578T Alpelisib
3.33
uM
LJP5
 2
N02
 72
hr
 765 2469 3124 0.7902 0.7222
MCF 10A Alpelisib
3.33
uM
LJP5
 3
N02
 72
hr
 1694 8141 11155 0.7298 0.6814
MDA-MB-231 Alpelisib
1.11
uM
LJP5
 1
N03
 72
hr
 1311 5059 5013 1.0091 1.0123
BT-20 Alpelisib
10.0
uM
LJP5
 3
N01
 72
hr
 1334 936 3970 0.2357 -0.1512
MDA-MB-231 Alpelisib
0.37
uM
LJP5
 1
N04
 72
hr
 1311 5236 5013 1.0444 1.0601