LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Relative Growth Rate After Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | GW843682X | 3.33 | uM | LJP6 | 2 | B14 | 72 | hr | 1694 | 918 | 11155 | 0.0823 | -0.0820 |
| BT-20 | CGP60474 | 3.33 | uM | LJP6 | 2 | G02 | 72 | hr | 1334 | 328 | 3970 | 0.0826 | -0.3819 |
| MCF7 | CGP60474 | 3.33 | uM | LJP6 | 3 | G02 | 72 | hr | 1389 | 469 | 5667 | 0.0827 | -0.2150 |
| MCF 10A | Radicicol | 10.0 | uM | LJP6 | 2 | K07 | 72 | hr | 1694 | 925 | 11155 | 0.0829 | -0.0813 |
| BT-20 | AT-7519 | 10.0 | uM | LJP6 | 3 | K01 | 72 | hr | 1334 | 329 | 3970 | 0.0829 | -0.3815 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 3 | K02 | 72 | hr | 1389 | 472 | 5667 | 0.0833 | -0.2143 |
| MCF7 | Alvocidib | 0.37 | uM | LJP6 | 2 | A16 | 72 | hr | 1389 | 474 | 5667 | 0.0836 | -0.2139 |
| MCF7 | CGP60474 | 0.37 | uM | LJP5 | 3 | F04 | 72 | hr | 1389 | 474 | 5667 | 0.0836 | -0.2139 |
| Hs 578T | Fedratinib | 10.0 | uM | LJP5 | 3 | L01 | 72 | hr | 765 | 262 | 3124 | 0.0839 | -0.2132 |
| Hs 578T | Canertinib | 10.0 | uM | LJP6 | 2 | H07 | 72 | hr | 765 | 262 | 3124 | 0.0839 | -0.2132 |
| MCF7 | WZ3105 | 10.0 | uM | LJP5 | 3 | D19 | 72 | hr | 1389 | 476 | 5667 | 0.0840 | -0.2134 |
| MCF 10A | Geldanamycin | 3.33 | uM | LJP6 | 3 | O02 | 72 | hr | 1694 | 938 | 11155 | 0.0841 | -0.0799 |
| Hs 578T | CGP60474 | 10.0 | uM | LJP6 | 3 | G01 | 72 | hr | 765 | 263 | 3124 | 0.0842 | -0.2128 |
| MCF 10A | A443654 | 3.33 | uM | LJP6 | 1 | I20 | 72 | hr | 1694 | 939 | 11155 | 0.0842 | -0.0798 |
| BT-20 | Mitoxantrone | 10.0 | uM | LJP5 | 1 | C19 | 72 | hr | 1334 | 335 | 3970 | 0.0844 | -0.3792 |
| MCF7 | Alvocidib | 10.0 | uM | LJP6 | 1 | A13 | 72 | hr | 1389 | 479 | 5667 | 0.0845 | -0.2127 |
| MCF 10A | Dasatinib | 10.0 | uM | LJP6 | 2 | I01 | 72 | hr | 1694 | 946 | 11155 | 0.0848 | -0.0791 |
| MCF7 | WZ3105 | 0.12 | uM | LJP5 | 1 | D23 | 72 | hr | 1389 | 482 | 5667 | 0.0850 | -0.2120 |
| BT-20 | CGP60474 | 10.0 | uM | LJP6 | 3 | G01 | 72 | hr | 1334 | 338 | 3970 | 0.0851 | -0.3781 |
| MCF 10A | BI-2536 | 0.12 | uM | LJP6 | 3 | D17 | 72 | hr | 1694 | 951 | 11155 | 0.0852 | -0.0786 |
| MCF7 | A443654 | 10.0 | uM | LJP6 | 1 | I19 | 72 | hr | 1389 | 484 | 5667 | 0.0854 | -0.2115 |
| Hs 578T | CGP60474 | 3.33 | uM | LJP6 | 2 | G02 | 72 | hr | 765 | 267 | 3124 | 0.0855 | -0.2111 |
| MCF7 | Mitoxantrone | 3.33 | uM | LJP6 | 2 | C20 | 72 | hr | 1389 | 485 | 5667 | 0.0856 | -0.2113 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 3 | A14 | 72 | hr | 1389 | 485 | 5667 | 0.0856 | -0.2113 |
| MCF7 | Alvocidib | 3.33 | uM | LJP6 | 2 | A14 | 72 | hr | 1389 | 486 | 5667 | 0.0857 | -0.2111 |