LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
Hs 578T PHA-793887
0.04
uM
LJP6
 3
E24
 72
hr
 765 1599 3124 0.5118 0.3535
MCF 10A Afatinib
1.11
uM
LJP6
 2
G21
 72
hr
 1694 1785 11155 0.1600 0.0096
MDA-MB-231 Sirolimus
0.37
uM
LJP6
 1
L16
 72
hr
 1311 4414 5013 0.8804 0.8381
MDA-MB-231 Sorafenib
0.37
uM
LJP6
 2
B10
 72
hr
 1311 5207 5013 1.0386 1.0523
MDA-MB-231 Torin1
0.37
uM
LJP6
 3
O16
 72
hr
 1311 2135 5013 0.4259 0.2224
MDA-MB-231 Torin1
0.37
uM
LJP6
 1
O16
 72
hr
 1311 1919 5013 0.3828 0.1641
MDA-MB-231 Torin1
0.37
uM
LJP6
 2
O16
 72
hr
 1311 1900 5013 0.3790 0.1589
MDA-MB-231 BMS345541
1.11
uM
LJP6
 3
D03
 72
hr
 1311 3823 5013 0.7625 0.6784
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 2
A15
 72
hr
 1311 773 5013 0.1542 -0.1455
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 2
P10
 72
hr
 1311 3409 5013 0.6800 0.5666
MDA-MB-231 Withaferin A
0.37
uM
LJP6
 3
G16
 72
hr
 1311 3521 5013 0.7023 0.5968
MDA-MB-231 XMD11-50
0.37
uM
LJP6
 1
P10
 72
hr
 1311 3686 5013 0.7352 0.6414
MDA-MB-231 Alvocidib
1.11
uM
LJP6
 1
A15
 72
hr
 1311 765 5013 0.1526 -0.1477
MDA-MB-231 ZSTK474
0.37
uM
LJP6
 2
M16
 72
hr
 1311 3376 5013 0.6734 0.5576
MDA-MB-231 Afatinib
1.11
uM
LJP6
 3
G21
 72
hr
 1311 3493 5013 0.6967 0.5893
MDA-MB-231 BMS345541
1.11
uM
LJP6
 2
D03
 72
hr
 1311 3700 5013 0.7380 0.6452
MDA-MB-231 AZD 5438
1.11
uM
LJP6
 1
J03
 72
hr
 1311 1210 5013 0.2414 -0.0275
MDA-MB-231 AT-7519
1.11
uM
LJP6
 1
K03
 72
hr
 1311 787 5013 0.1570 -0.1418
MDA-MB-231 AT-7519
1.11
uM
LJP6
 3
K03
 72
hr
 1311 761 5013 0.1518 -0.1488
MDA-MB-231 BMS345541
1.11
uM
LJP6
 1
D03
 72
hr
 1311 3861 5013 0.7701 0.6887
MDA-MB-231 AZD7762
1.11
uM
LJP6
 2
L03
 72
hr
 1311 1205 5013 0.2404 -0.0288
MDA-MB-231 BI-2536
1.11
uM
LJP6
 3
D15
 72
hr
 1311 1221 5013 0.2435 -0.0245