LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 2 of 15: Cell count and relative growth within biological replicate 2. - Dataset (ID:20238)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit LJP Library Plate Replicate Assay Well Timepoint Timepoint Unit Total Cell Count Before Treatment Total Cell Count After Treatment Total Control Cell Count Relative Cell Count Relative Growth Rate After Treatment
SK-BR-3 XMD11-85h
0.04
uM
LJP6
 2
P24
 72
hr
 2543 4127 5578 0.7398 0.5217
MCF 10A Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 1694 2800 11155 0.2510 0.1169
MCF 10A Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 1694 2568 11155 0.2302 0.0923
SK-BR-3 XMD11-85h
0.04
uM
LJP6
 1
P24
 72
hr
 2543 4083 5578 0.7319 0.5072
MCF7 XMD11-85h
0.04
uM
LJP6
 1
P24
 72
hr
 1389 3116 5667 0.5498 0.4036
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 1
P24
 72
hr
 1311 3724 5013 0.7428 0.6517
Hs 578T Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 765 1218 3124 0.3898 0.1920
SK-BR-3 XMD11-85h
0.04
uM
LJP6
 3
P24
 72
hr
 2543 3925 5578 0.7036 0.4552
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 3
P24
 72
hr
 1311 3785 5013 0.7550 0.6681
MDA-MB-231 XMD11-85h
0.04
uM
LJP6
 2
P24
 72
hr
 1311 3936 5013 0.7851 0.7089
BT-20 Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 1334 3109 3970 0.7829 0.6731
MCF7 XMD11-85h
0.04
uM
LJP6
 3
P24
 72
hr
 1389 4594 5667 0.8105 0.7490
MCF 10A Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 1694 2900 11155 0.2600 0.1274
SK-BR-3 Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 2543 3447 5578 0.6179 0.2977
BT-20 Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 1334 3431 3970 0.8640 0.7952
MCF7 Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 1389 2625 5667 0.4631 0.2889
MDA-MB-231 Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 1311 1530 5013 0.3052 0.0590
BT-20 Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 1334 2925 3970 0.7366 0.6033
MDA-MB-231 Trametinib
0.04
uM
LJP5
 2
P24
 72
hr
 1311 1592 5013 0.3175 0.0757
MCF7 Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 1389 2744 5667 0.4841 0.3167
SK-BR-3 Trametinib
0.04
uM
LJP5
 1
P24
 72
hr
 2543 3405 5578 0.6104 0.2839
MDA-MB-231 Trametinib
0.04
uM
LJP5
 3
P24
 72
hr
 1311 1672 5013 0.3335 0.0973