Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
RA2708 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 2
IFN-g
 79.0 87
N2759 IL-1 alpha 100
ng/mL
 1
IL-4
 72.0 55
RA2708 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IFN-g
 60.0 68
RA1869 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
RANTES
 84.0 61
N2759 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
RANTES
 425.5 58
N2759 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
RANTES
 25.0 61
N2586 5z-7-oxozeaenol 0.6
uM
 IL-1 alpha 100
ng/mL
 1
RANTES
 44.0 48
RA1931 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
RANTES
 191.0 45
RA1869 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
RANTES
 5213.0 53
N2586 IKK16 2.0
uM
 IL-1 alpha 100
ng/mL
 1
RANTES
 630.5 44
RA1931 IL-1 alpha 100
ng/mL
 1
RANTES
 6029.0 52
RA1931 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
RANTES
 6069.0 39
N2586 IL-1 alpha 100
ng/mL
 1
RANTES
 12157.0 48
N2586 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 1
RANTES
 12879.0 61
N2645 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 2
IL-4
 34.5 60
RA1869 IL-1 alpha 100
ng/mL
 3
IL-5
 10.0 67
N2759 IL-1 alpha 100
ng/mL
 3
IL-5
 10.5 64
RA1931 IL-1 alpha 100
ng/mL
 3
IL-5
 10.0 73
N2586 IL-1 alpha 100
ng/mL
 3
IL-5
 9.0 57
RA1869 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 10.0 47
RA1869 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 9.0 51
N2759 JNK-IN-8 3.0
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 10.0 67
N2759 PH-797804 0.6
uM
 IL-1 alpha 100
ng/mL
 3
IL-5
 12.0 55
N2645 IL-1 alpha 100
ng/mL
 4
IL-7
 22.5 70
N2645 Tofacitinib 0.3
uM
 IL-1 alpha 100
ng/mL
 4
IL-7
 21.0 59