Synovial Fibroblast 3.2: Secretion response of seven primary human synovial fibroblast samples from healthy and rheumatoid arthritis-diagnosed donors to a panel of 3 stimuli and 5 small molecule inhibitors (replicate 2 of 2) - Dataset (ID:20235)
- Detail
- Small Molecules Studied
- Primary Cells Studied
- Proteins Studied
- Unclassified Perturbagens Studied
- Data Columns
- Results
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein Stimulus | Other Stimulus | Stimulus Concentration | Stimulus Conc Unit | ExpPlate | Measured Protein | Measured Protein MFI (a.u.) | Bead Count |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 0 | MMP-2 | 5.0 | 31 | ||||||||
| 0 | MMP-2 | 5.5 | 46 | ||||||||
| 0 | MMP-2 | 5.5 | 18 | ||||||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-2 | 5.5 | 34 | |||||
| 0 | MMP-2 | 5.5 | 20 | ||||||||
| N2586 | JNK-IN-8 | 3.0 | uM | 1 | MMP-1 | 6.0 | 51 | ||||
| 0 | MMP-2 | 6.0 | 25 | ||||||||
| 0 | IL-7 | 6.0 | 61 | ||||||||
| 0 | MMP-2 | 6.0 | 27 | ||||||||
| 0 | MMP-2 | 6.0 | 42 | ||||||||
| TNF-a | 100 | ng/mL | 0 | MMP-2 | 6.0 | 46 | |||||
| TNF-a | 100 | ng/mL | 0 | MMP-2 | 6.0 | 29 | |||||
| 0 | MMP-2 | 6.0 | 41 | ||||||||
| 0 | MMP-2 | 6.5 | 48 | ||||||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-2 | 6.5 | 22 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-2 | 7.0 | 39 | |||||
| IL-1 alpha | 100 | ng/mL | 0 | MMP-2 | 7.0 | 40 | |||||
| Poly(I:C) | 2 | ug/mL | 0 | MMP-2 | 7.0 | 32 | |||||
| 0 | IL-7 | 7.0 | 63 | ||||||||
| RA1931 | PH-797804 | 0.6 | uM | 3 | IL-5 | 7.0 | 51 | ||||
| RA1869 | 1 | IL-1B | 7.0 | 55 | |||||||
| RA1869 | 3 | IL-5 | 7.0 | 53 | |||||||
| RA1931 | Tofacitinib | 0.3 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-5 | 7.5 | 56 | |
| N2759 | 5z-7-oxozeaenol | 0.6 | uM | IL-1 alpha | 100 | ng/mL | 1 | IL-5 | 8.0 | 63 | |
| N2645 | 5z-7-oxozeaenol | 0.6 | uM | 2 | IL-5 | 8.0 | 68 |