Synovial Fibroblast 1: Secretion response of primary human synovial fibroblast samples from one healthy and one rheumatoid arthritis donor to a panel of 10 stimuli and 10 small molecule inhibitors - Dataset (ID:20233)

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Cell Small Molecule Small Mol Concentration Small Mol Conc Unit Protein Stimulus Other Stimulus Stimulus Concentration Stimulus Conc Unit ExpPlate Measured Protein Measured Protein MFI (a.u.) Bead Count
N2586 Ruxolitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 8779.0 62
N2586 EO1428 1.0
uM
 4
MIP-1B
 56.0 65
N2586 Tofacitinib 0.3
uM
 TNF-a 100
ng/mL
 3
IL-6
 8762.0 53
N2586 PI103 0.1
uM
 4
MIP-1B
 59.0 63
N2586 IKK16 2.0
uM
 TNF-a 100
ng/mL
 3
IL-6
 25570.0 61
N2586 JNK-IN-11 0.3
uM
 4
IL-5
 8.5 64
N2586 EO1428 1.0
uM
 3
IL-6
 7482.0 70
N2586 IGF-I 100
ug/mL
 2
IL-1RA
 20.5 64
N2586 EO1428 1.0
uM
 IGF-I 100
ug/mL
 2
IL-1RA
 22.0 69
N2586 PI103 0.1
uM
 IGF-I 100
ug/mL
 2
IL-1RA
 17.0 48
N2586 Sigma A6730 3.0
uM
 IGF-I 100
ug/mL
 2
IL-1RA
 21.0 59
N2586 JNK-IN-8 3.0
uM
 IGF-I 100
ug/mL
 2
IL-1RA
 24.0 68
N2586 JNK-IN-11 0.3
uM
 IGF-I 100
ug/mL
 2
IL-1RA
 20.0 49
N2586 2
IL-1RA
 11.0 41
N2586 JNK-IN-11 0.3
uM
 4
MIP-1B
 59.0 75
N2586 1
GM-CSF
 311.0 39
N2586 PD184352 0.1
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 397.0 50
N2586 Lestaurtinib 0.3
uM
 TNF-a 100
ng/mL
 1
GM-CSF
 356.0 46
N2586 IKK16 2.0
uM
 4
MIP-1B
 60.0 58
N2586 EO1428 1.0
uM
 1
GM-CSF
 403.0 31
N2586 Adiponectin 5
ng/mL
 2
IL-1RA
 22.0 66
N2586 EO1428 1.0
uM
 Adiponectin 5
ng/mL
 2
IL-1RA
 22.5 50
N2586 PI103 0.1
uM
 Adiponectin 5
ng/mL
 2
IL-1RA
 25.0 44
N2586 PI103 0.1
uM
 IL-17A 100
ng/mL
 2
RANTES
 66.5 68
N2586 EO1428 1.0
uM
 IL-17A 100
ng/mL
 2
RANTES
 266.0 66