Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 5.0 | ng/ml | 2 | -5.53 | 404.8037 | 0.065 | 0.83770 | 0.38743 | ||||||
| HeLa ICRP | TNF10 | 500.0 | ng/ml | 2 | -4.28 | 54.6429 | 0.065 | 0.87415 | 0.83163 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | ng/ml | anti-Fc | 25.0 | ng/ml | 1 | -5.30 | 298.2392 | 0.073 | 0.94086 | 0.48387 | |||
| HeLa ICRP | Bortezomib | 100 | nM | Mapatumumab | 10.0 | nM | 2 | -5.47 | 319.6967 | 0.075 | 0.86936 | 0.30949 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | ng/ml | anti-Fc | 25.0 | ng/ml | 5 | -5.44 | 331.4063 | 0.076 | 0.91071 | 0.41295 | |||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | ng/ml | anti-Fc | 25.0 | ng/ml | 2 | -5.36 | 315.9300 | 0.077 | 0.87923 | 0.49275 | |||
| HeLa ICRP | TNF10 | 500.0 | ng/ml | 4 | -4.31 | 68.7177 | 0.082 | 0.88147 | 0.86207 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | nM | 2 | -5.39 | 331.3306 | 0.083 | 0.86694 | 0.49064 | ||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 2 | -4.42 | 90.1432 | 0.101 | 0.89648 | 0.87225 | |||||||||
| HeLa ICRP Bcl-2-mCherry | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 1 | -4.09 | 48.5371 | 0.114 | 0.85590 | 0.76419 | ||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 5 | -4.38 | 78.5577 | 0.120 | 0.83894 | 0.82212 | |||||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 50.0 | ng/ml | 1 | -4.78 | 147.7273 | 0.121 | 0.93939 | 0.78788 | ||||||
| HeLa ICRP FLIP-L-mCherry | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 1 | -5.13 | 210.4954 | 0.132 | 0.56697 | 0.47890 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 50.0 | ng/ml | 2 | -4.89 | 170.8451 | 0.162 | 0.91080 | 0.78169 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | Apomab | 25.0 | ng/ml | anti-Fc | 25.0 | ng/ml | 4 | -5.56 | 395.2990 | 0.163 | 0.92691 | 0.51163 | |||
| HeLa ICRP FLIP-L-mCherry | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 2 | -5.11 | 216.4074 | 0.167 | 0.65556 | 0.58889 | ||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 7.5 | ng/ml | 2 | -5.69 | 426.8136 | 0.208 | 0.91182 | 0.36673 | ||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | anti-Fc | 100.0 | nM | 3 | -4.54 | 86.0039 | 0.218 | 0.84016 | 0.79337 | ||||||
| HeLa ICRP | Mapatumumab | 200.0 | nM | anti-Fc | 200.0 | nM | 1 | -4.52 | 86.0180 | 0.228 | 0.82635 | 0.80040 | ||||||
| HeLa ICRP Bcl-2-mCherry | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 2 | -4.04 | 46.3426 | 0.231 | 0.80556 | 0.63889 | ||||||
| HeLa ICRP | Mapatumumab | 25.0 | nM | anti-Fc | 25.0 | nM | 3 | -4.54 | 92.8286 | 0.238 | 0.83860 | 0.78369 | ||||||
| HeLa ICRP Bcl-XL-mCherry | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 1 | -4.11 | 52.2500 | 0.239 | 0.76111 | 0.66111 | ||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 25.0 | ng/ml | 1 | -5.21 | 240.5391 | 0.249 | 0.91826 | 0.63304 | ||||||
| HeLa ICRP | Mapatumumab | 25.0 | nM | anti-Fc | 25.0 | nM | 1 | -4.50 | 85.1585 | 0.268 | 0.73592 | 0.70775 | ||||||
| HeLa ICRP FLIP-L-mCherry | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 3 | -5.43 | 292.5407 | 0.270 | 0.61564 | 0.35505 |