Live-cell imaging of cell-to-cell variability in caspase-8 FRET reporter activity and cell fate trajectory modeling - Dataset (ID:20232)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Protein | Protein Concentration | Protein Conc Unit | Antibody Name | Antibody Concentration | Antibody Conc Unit | 2nd Antibody Name | 2nd Antibody Concentration | 2nd Antibody Conc Unit | Replicate | Mean log10(k) (a.u.) | Mean tau (min) | Surviving Fraction | Classification Accuracy (theta_T) | Classification Accuracy (fate boundary) |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 5 | -4.01 | 69.8361 | 0.836 | 0.18033 | 0.13115 | |||||||||
| HeLa ICRP | Navitoclax | 10 | uM | TNF10 | 250.0 | ng/ml | 1 | -4.39 | 70.4229 | 0.016 | 0.98363 | 0.90177 | ||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 500.0 | ng/ml | 1 | -4.04 | 70.9259 | 0.864 | 0.20988 | 0.13580 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 500.0 | ng/ml | 2 | -4.31 | 71.7160 | 0.000 | 0.97284 | 0.94815 | ||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 500.0 | ng/ml | 2 | -4.02 | 73.1522 | 0.880 | 0.19565 | 0.08696 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 4 | -4.04 | 75.6780 | 0.898 | 0.18644 | 0.10169 | |||||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 5 | -4.03 | 76.7361 | 0.792 | 0.22222 | 0.20833 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 4 | -4.05 | 77.8723 | 0.936 | 0.12766 | 0.10638 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 5 | -4.38 | 78.5577 | 0.120 | 0.83894 | 0.82212 | |||||||||
| HeLa ICRP Bcl-XL-mCherry | TNF10 | 250.0 | ng/ml | 2 | -4.19 | 81.1458 | 0.917 | 0.25000 | 0.08333 | |||||||||
| HeLa ICRP | Bortezomib | 100 | nM | TNF10 | 250.0 | ng/ml | 2 | -4.37 | 81.7724 | 0.002 | 0.99067 | 0.94403 | ||||||
| HeLa ICRP | Mapatumumab | 10.0 | nM | anti-Fc | 10.0 | nM | 1 | -4.49 | 83.0851 | 0.309 | 0.68617 | 0.65691 | ||||||
| HeLa ICRP Bcl-2-mCherry | TNF10 | 250.0 | ng/ml | 2 | -4.15 | 84.0957 | 0.777 | 0.25532 | 0.22340 | |||||||||
| HeLa ICRP | Mapatumumab | 25.0 | nM | anti-Fc | 25.0 | nM | 1 | -4.50 | 85.1585 | 0.268 | 0.73592 | 0.70775 | ||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | anti-Fc | 100.0 | nM | 3 | -4.54 | 86.0039 | 0.218 | 0.84016 | 0.79337 | ||||||
| HeLa ICRP | Mapatumumab | 200.0 | nM | anti-Fc | 200.0 | nM | 1 | -4.52 | 86.0180 | 0.228 | 0.82635 | 0.80040 | ||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | anti-Fc | 100.0 | nM | 1 | -4.50 | 87.7636 | 0.273 | 0.80364 | 0.73091 | ||||||
| HeLa ICRP | Mapatumumab | 100.0 | nM | anti-Fc | 100.0 | nM | 2 | -4.57 | 88.4746 | 0.369 | 0.65085 | 0.66780 | ||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 1 | -4.43 | 88.9362 | 0.060 | 0.90780 | 0.91064 | |||||||||
| HeLa ICRP | TNF10 | 250.0 | ng/ml | 2 | -4.42 | 90.1432 | 0.101 | 0.89648 | 0.87225 | |||||||||
| HeLa ICRP | Mapatumumab | 25.0 | nM | anti-Fc | 25.0 | nM | 2 | -4.55 | 92.1239 | 0.381 | 0.66372 | 0.64307 | ||||||
| HeLa ICRP | Mapatumumab | 25.0 | nM | anti-Fc | 25.0 | nM | 3 | -4.54 | 92.8286 | 0.238 | 0.83860 | 0.78369 | ||||||
| HeLa ICRP FLIP-L-mCherry | TNF10 | 250.0 | ng/ml | 4 | -4.83 | 93.5600 | 0.792 | 0.91200 | 0.63200 | |||||||||
| HeLa ICRP FLIP-L-mCherry | TNF10 | 500.0 | ng/ml | 2 | -4.74 | 96.0930 | 0.721 | 0.87442 | 0.62326 | |||||||||
| HeLa ICRP FLIP-L-mCherry | TNF10 | 250.0 | ng/ml | 2 | -4.76 | 97.0362 | 0.796 | 0.86878 | 0.59276 |