PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
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| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| WM-115 | 5 | hr | Bim | -2.55830 | 2.48160 |
| C32 | 24 | hr | Bim | -5.80310 | 0.97812 |
| LOXIMVI | 1 | hr | Bim | 3.58210 | -0.86495 |
| K2 | 5 | hr | Bim | -2.41500 | 0.90851 |
| COLO 858 | 1 | hr | Bim | 2.45530 | -0.58283 |
| C32 | 1 | hr | Bim | -0.20113 | -0.07848 |
| K2 | 1 | hr | Bim | 0.48026 | 0.28118 |
| C32 | 48 | hr | Bim | -8.07140 | 0.97247 |
| C32 | 5 | hr | Bim | -2.63110 | -0.01033 |
| LOXIMVI | 10 | hr | Bim | 3.08970 | -0.95133 |
| LOXIMVI | 48 | hr | Bim | 0.06177 | -0.87670 |
| MZ7-mel | 1 | hr | Bim | -0.31133 | -0.07806 |
| LOXIMVI | 24 | hr | Bim | 0.58901 | 2.15340 |
| MZ7-mel | 48 | hr | Bim | -7.96560 | 2.16190 |
| RVH-421 | 1 | hr | Bim | 1.78350 | -2.61950 |
| MMAC-SF | 1 | hr | Bim | 2.33420 | -1.14560 |
| C32 | 10 | hr | Bim | -2.40770 | 0.07521 |
| COLO 858 | 24 | hr | Bim | -7.49980 | -0.74041 |
| K2 | 10 | hr | Bim | -0.56647 | 0.76614 |
| COLO 858 | 48 | hr | Bim | 0.82671 | -0.20180 |
| K2 | 24 | hr | Bim | -5.83140 | -0.01586 |
| COLO 858 | 10 | hr | Bim | -0.35083 | -0.53756 |
| COLO 858 | 5 | hr | Bim | -3.24470 | -0.37663 |
| WM1552C | 48 | hr | Bim | 2.39580 | -2.69920 |
| WM1552C | 24 | hr | Bim | -2.77770 | -3.72120 |