PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
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| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| COLO 858 | 24 | hr | p-HSP27(S82) | -1.41810 | -2.15680 |
| MZ7-mel | 5 | hr | p-Histone H3(S10) | -1.40670 | -0.84482 |
| WM1552C | 5 | hr | p-p90RSK(S380) | -1.40520 | 0.28846 |
| WM1552C | 5 | hr | p-JNK(T183/Y185) | -1.38780 | 0.27630 |
| WM-115 | 24 | hr | p-AKT(T308) | -1.36980 | 2.28720 |
| COLO 858 | 24 | hr | p-p90RSK(T573) | -1.36010 | -0.25342 |
| SKMEL28 | 24 | hr | p-AKT(S473) | -1.34760 | -0.68072 |
| C32 | 10 | hr | p-AMPK(T172) | -1.34300 | 0.31521 |
| SKMEL28 | 48 | hr | p-HSP27(S82) | -1.32470 | -1.72500 |
| C32 | 10 | hr | p-P38(T180/Y182) | -1.32110 | 0.46039 |
| WM-115 | 10 | hr | p-AKT(T308) | -1.31350 | 2.68290 |
| C32 | 10 | hr | p-p90RSK(T573) | -1.31020 | -0.00316 |
| C32 | 48 | hr | p-p90RSK(T573) | -1.30300 | -1.19070 |
| C32 | 5 | hr | p-Histone H3(S10) | -1.29620 | 0.23172 |
| WM-115 | 24 | hr | p-NFKB(S536) | -1.29040 | 1.92940 |
| C32 | 1 | hr | p-AKT(S473) | -1.28370 | -2.03900 |
| MZ7-mel | 48 | hr | p-AKT(S473) | -1.25220 | 2.14980 |
| WM-115 | 5 | hr | p-cJun(S63) | -1.24780 | 1.88260 |
| WM1552C | 48 | hr | p-cJun(S63) | -1.23800 | -3.28480 |
| RVH-421 | 48 | hr | p-mTOR(S2448) | -1.22350 | -1.91150 |
| MZ7-mel | 10 | hr | p27 Kip1 | -1.21760 | 0.21346 |
| K2 | 5 | hr | p-HSP27(S82) | -1.21420 | 0.86781 |
| MMAC-SF | 5 | hr | p-Histone H3(S10) | -1.20870 | -0.19727 |
| COLO 858 | 24 | hr | p-p90RSK(S380) | -1.20110 | 0.32008 |
| MZ7-mel | 48 | hr | p-JNK(T183/Y185) | -1.19750 | 2.45520 |