PLSR model loadings (pMEK and pERK excluded) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20230)
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| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| C32 | 48 | hr | cPARP | -9.15590 | -2.27710 |
| MMAC-SF | 24 | hr | p27 Kip1 | -8.74820 | -2.17230 |
| C32 | 48 | hr | Bim | -8.07140 | 0.97247 |
| C32 | 48 | hr | p-AMPK(T172) | -8.05440 | -1.13410 |
| K2 | 48 | hr | p27 Kip1 | -8.04770 | 0.19757 |
| MZ7-mel | 48 | hr | Bim | -7.96560 | 2.16190 |
| MMAC-SF | 24 | hr | Bim | -7.79580 | -1.41500 |
| C32 | 48 | hr | p27 Kip1 | -7.76980 | -0.16574 |
| C32 | 48 | hr | p-AKT(T308) | -7.52260 | 0.08243 |
| MZ7-mel | 48 | hr | p27 Kip1 | -7.50270 | 3.06240 |
| COLO 858 | 24 | hr | Bim | -7.49980 | -0.74041 |
| K2 | 48 | hr | p-cJun(S63) | -7.31170 | -0.15137 |
| COLO 858 | 24 | hr | p-AKT(T308) | -7.18280 | 0.63035 |
| MMAC-SF | 24 | hr | cPARP | -7.08530 | -1.69720 |
| MMAC-SF | 24 | hr | p-HSP27(S82) | -7.08160 | 0.14567 |
| K2 | 48 | hr | p-NFKB(S536) | -7.07520 | 0.67174 |
| MZ7-mel | 48 | hr | cPARP | -7.02990 | 3.35310 |
| K2 | 48 | hr | p-AKT(S473) | -7.01060 | -0.03858 |
| COLO 858 | 24 | hr | p27 Kip1 | -6.87460 | -0.98048 |
| K2 | 48 | hr | cPARP | -6.86990 | 1.03120 |
| RVH-421 | 24 | hr | cPARP | -6.86810 | -0.15272 |
| MMAC-SF | 24 | hr | p-cJun(S63) | -6.83530 | -0.32545 |
| SKMEL28 | 48 | hr | p27 Kip1 | -6.78830 | -1.77840 |
| K2 | 48 | hr | Bim | -6.67520 | 0.27411 |
| COLO 858 | 24 | hr | p-JNK(T183/Y185) | -6.66110 | 0.32344 |