PLSR model loadings (pMEK and pERK included) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20229)
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| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| K2 | 48 | hr | Bim | -5.80920 | -0.89063 |
| K2 | 5 | hr | Bim | -2.07340 | -0.07290 |
| COLO 858 | 10 | hr | Bim | -0.23085 | -1.16470 |
| LOXIMVI | 1 | hr | Bim | 1.89310 | -0.30201 |
| MMAC-SF | 10 | hr | Bim | 0.63646 | -0.74968 |
| LOXIMVI | 5 | hr | Bim | 0.05776 | 1.61040 |
| MMAC-SF | 48 | hr | Bim | 0.07707 | -0.33320 |
| C32 | 10 | hr | Bim | -0.77867 | -0.16369 |
| MZ7-mel | 5 | hr | Bim | -1.54470 | -1.36110 |
| C32 | 1 | hr | Bim | -0.02802 | -0.10082 |
| K2 | 10 | hr | Bim | -0.41460 | -0.32815 |
| COLO 858 | 1 | hr | Bim | 2.01710 | -1.17000 |
| C32 | 5 | hr | Bim | -0.88685 | -0.00581 |
| COLO 858 | 48 | hr | Bim | 0.76269 | -1.67370 |
| COLO 858 | 24 | hr | Bim | -6.02050 | -1.29730 |
| K2 | 1 | hr | Bim | 0.49984 | -0.39665 |
| MMAC-SF | 1 | hr | Bim | 1.44370 | -0.88061 |
| K2 | 24 | hr | Bim | -5.14450 | -0.22263 |
| LOXIMVI | 24 | hr | Bim | -0.11516 | 1.54930 |
| LOXIMVI | 48 | hr | Bim | -0.27225 | 0.23660 |
| SKMEL28 | 5 | hr | Bim | -1.79160 | 0.65481 |
| C32 | 48 | hr | Bim | -2.68240 | -0.47847 |
| COLO 858 | 5 | hr | Bim | -2.56010 | -1.58120 |
| WM1552C | 48 | hr | Bim | 0.90142 | -1.31470 |
| WM1552C | 24 | hr | Bim | -1.52830 | -1.75270 |