PLSR model loadings (pMEK and pERK included) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20229)
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| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| WM1552C | 1 | hr | p-p70S6K(T421/S424) | 1.55300 | -0.99489 |
| WM1552C | 1 | hr | p-mTOR(S2448) | 1.42720 | -0.75908 |
| WM1552C | 1 | hr | p-AKT(S473) | 0.54488 | -0.76362 |
| WM1552C | 1 | hr | p-AKT(T308) | 0.96300 | -1.16030 |
| WM1552C | 1 | hr | p-p90RSK(T573) | 0.97504 | -0.48370 |
| WM1552C | avg(48,72) | hr | Viability | 4.89960 | 1.35020 |
| WM1552C | 1 | hr | p-p90RSK(S380) | 1.04430 | -0.65084 |
| WM1552C | 1 | hr | pERK(T202/Y204) | 9.39050 | 0.68225 |
| WM1552C | 1 | hr | pMEK(S217/221) | 3.84420 | -1.55640 |
| WM1552C | 1 | hr | p-p70S6K(T389) | 1.58340 | -1.08260 |