PLSR model loadings (pMEK and pERK included) from analysis of the covariation of molecular signals with cell viability and apoptosis fraction in BRAF(V600E/D) melanoma cell lines - Dataset (ID:20229)
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| Cell Line | Time Point | Time Point Unit | Variable | PC1 Loading | PC2 Loading |
|---|---|---|---|---|---|
| MMAC-SF | avg(48,72) | hr | Viability | 4.97490 | 1.04360 |
| LOXIMVI | avg(48,72) | hr | Viability | 3.53370 | 2.20440 |
| RVH-421 | avg(48,72) | hr | Viability | 4.97890 | 0.83992 |
| SKMEL28 | avg(48,72) | hr | Viability | 4.68090 | 1.33340 |
| C32 | avg(48,72) | hr | Viability | 4.86600 | 1.54590 |
| COLO 858 | avg(48,72) | hr | Viability | 5.04880 | 0.60826 |
| K2 | 48 | hr | Viability | 4.04630 | 1.46130 |
| MZ7-mel | avg(48,72) | hr | Viability | 4.96100 | 1.18220 |
| WM1552C | avg(48,72) | hr | Viability | 4.89960 | 1.35020 |
| WM-115 | avg(48,72) | hr | Viability | 4.24100 | 2.15740 |
| MMAC-SF | 5 | hr | Total c-Jun | 0.83701 | 0.18951 |
| LOXIMVI | 48 | hr | Total c-Jun | 0.93653 | -0.48173 |
| K2 | 1 | hr | Total c-Jun | 0.98264 | -0.31780 |
| C32 | 10 | hr | Total c-Jun | 3.09320 | -0.06927 |
| LOXIMVI | 24 | hr | Total c-Jun | 1.70990 | -0.35062 |
| MMAC-SF | 1 | hr | Total c-Jun | 2.02800 | -0.26779 |
| MMAC-SF | 10 | hr | Total c-Jun | 3.47900 | -0.24757 |
| LOXIMVI | 1 | hr | Total c-Jun | 1.22670 | -0.57348 |
| C32 | 1 | hr | Total c-Jun | 0.54181 | 0.04245 |
| C32 | 5 | hr | Total c-Jun | 2.01540 | -0.30253 |
| C32 | 24 | hr | Total c-Jun | 2.14860 | 0.27793 |
| C32 | 48 | hr | Total c-Jun | 0.28580 | 0.66921 |
| COLO 858 | 5 | hr | Total c-Jun | -0.12139 | -0.41216 |
| COLO 858 | 24 | hr | Total c-Jun | -1.56820 | -0.92227 |
| LOXIMVI | 5 | hr | Total c-Jun | 0.97660 | 0.51354 |