Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
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| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2882.90 | p-Rb(S807/S811) | 203.40 | p-cJun(S73) | 97.65 | 1 | LOXIMVI-signal3 | F10 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 3032.30 | p-Rb(S807/S811) | 209.50 | p-cJun(S73) | 127.94 | 1 | LOXIMVI-signal3 | F11 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 2814.00 | p-Rb(S807/S811) | 96.96 | p-cJun(S73) | 30.63 | 1 | LOXIMVI-signal3 | F2 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 2.0000 | uM | 24 | hr | | Ki-67 | 2379.60 | p-Rb(S807/S811) | 93.92 | p-cJun(S73) | 26.61 | 1 | LOXIMVI-signal3 | F3 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.8000 | uM | 24 | hr | | Ki-67 | 2249.30 | p-Rb(S807/S811) | 93.65 | p-cJun(S73) | 24.47 | 1 | LOXIMVI-signal3 | F4 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.3200 | uM | 24 | hr | | Ki-67 | 2320.10 | p-Rb(S807/S811) | 113.12 | p-cJun(S73) | 29.40 | 1 | LOXIMVI-signal3 | F5 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.1280 | uM | 24 | hr | | Ki-67 | 2553.90 | p-Rb(S807/S811) | 157.20 | p-cJun(S73) | 41.82 | 1 | LOXIMVI-signal3 | F6 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0512 | uM | 24 | hr | | Ki-67 | 2628.70 | p-Rb(S807/S811) | 180.11 | p-cJun(S73) | 54.15 | 1 | LOXIMVI-signal3 | F7 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0205 | uM | 24 | hr | | Ki-67 | 2734.80 | p-Rb(S807/S811) | 188.75 | p-cJun(S73) | 65.47 | 1 | LOXIMVI-signal3 | F8 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0082 | uM | 24 | hr | | Ki-67 | 2742.00 | p-Rb(S807/S811) | 188.71 | p-cJun(S73) | 92.00 | 1 | LOXIMVI-signal3 | F9 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2829.00 | p-Rb(S807/S811) | 197.37 | p-cJun(S73) | 98.13 | 2 | LOXIMVI-signal3 | G10 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 2934.10 | p-Rb(S807/S811) | 203.26 | p-cJun(S73) | 120.51 | 2 | LOXIMVI-signal3 | G11 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 2767.00 | p-Rb(S807/S811) | 114.93 | p-cJun(S73) | 35.58 | 2 | LOXIMVI-signal3 | G2 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 2.0000 | uM | 24 | hr | | Ki-67 | 2231.10 | p-Rb(S807/S811) | 90.56 | p-cJun(S73) | 23.75 | 2 | LOXIMVI-signal3 | G3 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.8000 | uM | 24 | hr | | Ki-67 | 2219.70 | p-Rb(S807/S811) | 100.07 | p-cJun(S73) | 23.48 | 2 | LOXIMVI-signal3 | G4 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.3200 | uM | 24 | hr | | Ki-67 | 2301.20 | p-Rb(S807/S811) | 115.21 | p-cJun(S73) | 27.54 | 2 | LOXIMVI-signal3 | G5 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.1280 | uM | 24 | hr | | Ki-67 | 2465.90 | p-Rb(S807/S811) | 148.93 | p-cJun(S73) | 37.40 | 2 | LOXIMVI-signal3 | G6 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0512 | uM | 24 | hr | | Ki-67 | 2517.90 | p-Rb(S807/S811) | 172.29 | p-cJun(S73) | 48.52 | 2 | LOXIMVI-signal3 | G7 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0205 | uM | 24 | hr | | Ki-67 | 2617.50 | p-Rb(S807/S811) | 180.39 | p-cJun(S73) | 69.18 | 2 | LOXIMVI-signal3 | G8 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0082 | uM | 24 | hr | | Ki-67 | 2667.60 | p-Rb(S807/S811) | 189.57 | p-cJun(S73) | 84.40 | 2 | LOXIMVI-signal3 | G9 |