Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
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| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0512 | uM | 24 | hr | | Ki-67 | 2628.70 | p-Rb(S807/S811) | 180.11 | p-cJun(S73) | 54.15 | 1 | LOXIMVI-signal3 | F7 |
| Vemurafenib | LOXIMVI | 0.0512 | uM | 24 | hr | | Ki-67 | 2629.00 | p-Rb(S807/S811) | 170.98 | p-cJun(S73) | 89.13 | 2 | LOXIMVI-signal3 | C7 | |
| JNK-IN-8 | COLO 858 | 5.0000 | uM | 24 | hr | | Ki-67 | 2634.30 | p-Rb(S807/S811) | 252.91 | p-cJun(S73) | 39.50 | 2 | Colo858-signal3 | E2 | |
| JNK-IN-8 | COLO 858 | 2.0000 | uM | 24 | hr | | Ki-67 | 2641.30 | p-Rb(S807/S811) | 226.22 | p-cJun(S73) | 34.79 | 2 | Colo858-signal3 | E3 | |
| Vemurafenib | LOXIMVI | 0.1280 | uM | 24 | hr | | Ki-67 | 2653.30 | p-Rb(S807/S811) | 167.23 | p-cJun(S73) | 86.38 | 1 | LOXIMVI-signal3 | B6 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0082 | uM | 24 | hr | | Ki-67 | 2667.60 | p-Rb(S807/S811) | 189.57 | p-cJun(S73) | 84.40 | 2 | LOXIMVI-signal3 | G9 |
| Vemurafenib | LOXIMVI | 0.0512 | uM | 24 | hr | | Ki-67 | 2730.30 | p-Rb(S807/S811) | 177.84 | p-cJun(S73) | 95.29 | 1 | LOXIMVI-signal3 | B7 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0205 | uM | 24 | hr | | Ki-67 | 2734.80 | p-Rb(S807/S811) | 188.75 | p-cJun(S73) | 65.47 | 1 | LOXIMVI-signal3 | F8 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0082 | uM | 24 | hr | | Ki-67 | 2742.00 | p-Rb(S807/S811) | 188.71 | p-cJun(S73) | 92.00 | 1 | LOXIMVI-signal3 | F9 |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 2767.00 | p-Rb(S807/S811) | 114.93 | p-cJun(S73) | 35.58 | 2 | LOXIMVI-signal3 | G2 |
| Vemurafenib | LOXIMVI | 0.0205 | uM | 24 | hr | | Ki-67 | 2785.20 | p-Rb(S807/S811) | 185.62 | p-cJun(S73) | 96.25 | 1 | LOXIMVI-signal3 | B8 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 2814.00 | p-Rb(S807/S811) | 96.96 | p-cJun(S73) | 30.63 | 1 | LOXIMVI-signal3 | F2 |
| JNK-IN-8 | LOXIMVI | 0.0512 | uM | 24 | hr | | Ki-67 | 2817.60 | p-Rb(S807/S811) | 205.31 | p-cJun(S73) | 68.42 | 2 | LOXIMVI-signal3 | E7 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2829.00 | p-Rb(S807/S811) | 197.37 | p-cJun(S73) | 98.13 | 2 | LOXIMVI-signal3 | G10 |
| JNK-IN-8 | LOXIMVI | 0.0033 | uM | 24 | hr | | Ki-67 | 2844.80 | p-Rb(S807/S811) | 201.31 | p-cJun(S73) | 107.70 | 1 | LOXIMVI-signal3 | D10 | |
| JNK-IN-8 | LOXIMVI | 0.3200 | uM | 24 | hr | | Ki-67 | 2848.50 | p-Rb(S807/S811) | 207.66 | p-cJun(S73) | 57.32 | 2 | LOXIMVI-signal3 | E5 | |
| Vemurafenib | LOXIMVI | 0.0205 | uM | 24 | hr | | Ki-67 | 2858.70 | p-Rb(S807/S811) | 191.23 | p-cJun(S73) | 102.21 | 2 | LOXIMVI-signal3 | C8 | |
| JNK-IN-8 | LOXIMVI | 0.0082 | uM | 24 | hr | | Ki-67 | 2876.00 | p-Rb(S807/S811) | 199.31 | p-cJun(S73) | 94.47 | 2 | LOXIMVI-signal3 | E9 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 2882.90 | p-Rb(S807/S811) | 203.40 | p-cJun(S73) | 97.65 | 1 | LOXIMVI-signal3 | F10 |
| JNK-IN-8 | LOXIMVI | 0.1280 | uM | 24 | hr | | Ki-67 | 2886.70 | p-Rb(S807/S811) | 203.46 | p-cJun(S73) | 63.66 | 2 | LOXIMVI-signal3 | E6 | |
| Vemurafenib | LOXIMVI | 0.0082 | uM | 24 | hr | | Ki-67 | 2905.80 | p-Rb(S807/S811) | 198.95 | p-cJun(S73) | 109.56 | 1 | LOXIMVI-signal3 | B9 | |
| JNK-IN-8 | LOXIMVI | 0.1280 | uM | 24 | hr | | Ki-67 | 2922.80 | p-Rb(S807/S811) | 202.58 | p-cJun(S73) | 68.33 | 1 | LOXIMVI-signal3 | D6 | |
| JNK-IN-8 | LOXIMVI | 0.0033 | uM | 24 | hr | | Ki-67 | 2929.10 | p-Rb(S807/S811) | 208.63 | p-cJun(S73) | 107.76 | 2 | LOXIMVI-signal3 | E10 | |
| Vemurafenib | LOXIMVI | 0.0033 | uM | 24 | hr | | Ki-67 | 2929.90 | p-Rb(S807/S811) | 202.41 | p-cJun(S73) | 113.58 | 1 | LOXIMVI-signal3 | B10 | |
| Vemurafenib | LOXIMVI | JNK-IN-8 | 0.0000 | uM | 24 | hr | | Ki-67 | 2934.10 | p-Rb(S807/S811) | 203.26 | p-cJun(S73) | 120.51 | 2 | LOXIMVI-signal3 | G11 |