Phosphorylation state and protein levels measured in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20219)
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| Small Molecule | Cell Line | 2nd Drug | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Image | Measured Protein (Alexa Fluor 488) | Measured Protein Value (488) | Measured Protein (Alexa Fluor 568) | Measured Protein Value (568) | Measured Protein (Alexa Fluor 647) | Measured Protein Value (647) | Replicate | Plate Name | Plate Well |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vemurafenib | WM1552C | 0.0205 | uM | 24 | hr | | Ki-67 | 1588.20 | p-Rb(S807/S811) | 104.90 | p-cJun(S73) | 155.81 | 1 | WM1552C-signal3 | B8 | |
| JNK-IN-8 | WM1552C | 0.1280 | uM | 24 | hr | | Ki-67 | 1589.50 | p-Rb(S807/S811) | 107.97 | p-cJun(S73) | 133.56 | 2 | WM1552C-signal3 | E6 | |
| JNK-IN-8 | WM1552C | 2.0000 | uM | 24 | hr | | Ki-67 | 1645.70 | p-Rb(S807/S811) | 114.19 | p-cJun(S73) | 27.88 | 2 | WM1552C-signal3 | E3 | |
| Vemurafenib | WM1552C | 0.0033 | uM | 24 | hr | | Ki-67 | 1556.10 | p-Rb(S807/S811) | 107.86 | p-cJun(S73) | 143.87 | 1 | WM1552C-signal3 | B10 | |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.0033 | uM | 24 | hr | | Ki-67 | 1565.80 | p-Rb(S807/S811) | 107.30 | p-cJun(S73) | 143.22 | 2 | WM1552C-signal3 | G10 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.8000 | uM | 24 | hr | | Ki-67 | 1070.90 | p-Rb(S807/S811) | 51.39 | p-cJun(S73) | 29.77 | 1 | WM1552C-signal3 | F4 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.0082 | uM | 24 | hr | | Ki-67 | 1617.40 | p-Rb(S807/S811) | 105.76 | p-cJun(S73) | 149.70 | 1 | WM1552C-signal3 | F9 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.0082 | uM | 24 | hr | | Ki-67 | 1581.10 | p-Rb(S807/S811) | 104.30 | p-cJun(S73) | 145.59 | 2 | WM1552C-signal3 | G9 |
| Vemurafenib | WM1552C | 0.0205 | uM | 24 | hr | | Ki-67 | 1578.70 | p-Rb(S807/S811) | 105.13 | p-cJun(S73) | 151.66 | 2 | WM1552C-signal3 | C8 | |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.3200 | uM | 24 | hr | | Ki-67 | 1190.00 | p-Rb(S807/S811) | 68.22 | p-cJun(S73) | 96.63 | 2 | WM1552C-signal3 | G5 |
| JNK-IN-8 | WM1552C | 0.8000 | uM | 24 | hr | | Ki-67 | 1751.50 | p-Rb(S807/S811) | 114.25 | p-cJun(S73) | 56.72 | 2 | WM1552C-signal3 | E4 | |
| JNK-IN-8 | WM1552C | 0.0082 | uM | 24 | hr | | Ki-67 | 1586.10 | p-Rb(S807/S811) | 106.76 | p-cJun(S73) | 145.37 | 2 | WM1552C-signal3 | E9 | |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.3200 | uM | 24 | hr | | Ki-67 | 1190.30 | p-Rb(S807/S811) | 65.76 | p-cJun(S73) | 94.49 | 1 | WM1552C-signal3 | F5 |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.0205 | uM | 24 | hr | | Ki-67 | 1542.10 | p-Rb(S807/S811) | 107.52 | p-cJun(S73) | 159.51 | 2 | WM1552C-signal3 | G8 |
| Vemurafenib | WM1552C | JNK-IN-8 | 2.0000 | uM | 24 | hr | | Ki-67 | 974.64 | p-Rb(S807/S811) | 46.90 | p-cJun(S73) | 13.63 | 2 | WM1552C-signal3 | G3 |
| Vemurafenib | WM1552C | 0.0512 | uM | 24 | hr | | Ki-67 | 1451.30 | p-Rb(S807/S811) | 98.22 | p-cJun(S73) | 157.24 | 1 | WM1552C-signal3 | B7 | |
| Vemurafenib | WM1552C | 0.0000 | uM | 24 | hr | | Ki-67 | 1637.30 | p-Rb(S807/S811) | 105.15 | p-cJun(S73) | 139.30 | 2 | WM1552C-signal3 | C11 | |
| Vemurafenib | WM1552C | JNK-IN-8 | 5.0000 | uM | 24 | hr | | Ki-67 | 1101.80 | p-Rb(S807/S811) | 60.49 | p-cJun(S73) | 15.34 | 2 | WM1552C-signal3 | G2 |
| Vemurafenib | WM1552C | 0.8000 | uM | 24 | hr | | Ki-67 | 1044.70 | p-Rb(S807/S811) | 52.94 | p-cJun(S73) | 128.12 | 1 | WM1552C-signal3 | B4 | |
| Vemurafenib | WM1552C | 0.3200 | uM | 24 | hr | | Ki-67 | 1190.60 | p-Rb(S807/S811) | 70.53 | p-cJun(S73) | 155.05 | 1 | WM1552C-signal3 | B5 | |
| Vemurafenib | WM1552C | JNK-IN-8 | 0.1280 | uM | 24 | hr | | Ki-67 | 1366.10 | p-Rb(S807/S811) | 85.28 | p-cJun(S73) | 140.57 | 2 | WM1552C-signal3 | G6 |
| Vemurafenib | WM1552C | 0.0082 | uM | 24 | hr | | Ki-67 | 1538.30 | p-Rb(S807/S811) | 102.40 | p-cJun(S73) | 142.93 | 2 | WM1552C-signal3 | C9 | |
| JNK-IN-8 | WM1552C | 5.0000 | uM | 24 | hr | | Ki-67 | 1547.50 | p-Rb(S807/S811) | 115.39 | p-cJun(S73) | 22.53 | 1 | WM1552C-signal3 | D2 | |
| Vemurafenib | WM1552C | 0.8000 | uM | 24 | hr | | Ki-67 | 1017.40 | p-Rb(S807/S811) | 54.97 | p-cJun(S73) | 137.70 | 2 | WM1552C-signal3 | C4 | |
| Vemurafenib | WM1552C | 0.0000 | uM | 24 | hr | | Ki-67 | 1693.60 | p-Rb(S807/S811) | 110.42 | p-cJun(S73) | 138.63 | 1 | WM1552C-signal3 | B11 |